Table 2 Distribution of genotype and allele among RPL patients and controls
Study author | RPL cases | Healthy control | P-HWE | MAF | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
GG | GA | AA | G | A | GG | GA | AA | G | A | |||
Souza et al. [34] | 52 | 4 | 0 | 108 | 4 | 378 | 6 | 0 | 762 | 6 | 0/87 | 0/007 |
Brenner et al. [35] | 52 | 19 | 5 | 123 | 29 | 95 | 11 | 0 | 201 | 11 | 0/57 | 0/051 |
Wramsby et al. [36] | 51 | 10 | 1 | 112 | 12 | 67 | 2 | 0 | 136 | 2 | 0/9 | 0/014 |
Murphy et al. [52] | 39 | 2 | 0 | 80 | 2 | 527 | 13 | 0 | 1067 | 13 | 0/77 | 0/012 |
Pihusch et al. [33] | 94 | 8 | 0 | 196 | 8 | 117 | 11 | 0 | 245 | 11 | 0/61 | 0/042 |
Younis et al. | 63 | 12 | 3 | 138 | 18 | 131 | 8 | 0 | 270 | 8 | 0/72 | 0/028 |
Foka et al. [14] | 65 | 15 | 0 | 145 | 15 | 96 | 4 | 0 | 196 | 4 | 0/83 | 0/02 |
Rai et al. | 1037 | 72 | 2 | 2146 | 76 | 138 | 12 | 0 | 288 | 12 | 0/6 | 0/04 |
Carp et al. | 104 | 4 | 0 | 212 | 4 | 77 | 5 | 0 | 159 | 5 | 0/77 | 0/03 |
Finan et al. [38] | 65 | 38 | 7 | 168 | 52 | 56 | 11 | 0 | 123 | 11 | 0/46 | 0/082 |
Hohlagschwandtner et al. | 130 | 15 | 0 | 275 | 15 | 97 | 4 | 0 | 198 | 4 | 0/83 | 0/019 |
Pauer et al. [39] | 28 | 2 | 0 | 58 | 2 | 113 | 9 | 0 | 235 | 9 | 0/67 | 0/036 |
Mtiraoui et al. | 116 | 24 | 6 | 256 | 36 | 93 | 6 | 0 | 192 | 6 | 0/75 | 0/03 |
Aksoy et al. | 31 | 9 | 1 | 71 | 11 | 45 | 5 | 0 | 95 | 5 | 0/7 | 0/05 |
Mahjoub et al. [40] | 152 | 40 | 8 | 344 | 56 | 189 | 11 | 0 | 389 | 11 | 0/68 | 0/027 |
Ulukus et al. | 7 | 3 | 0 | 17 | 3 | 49 | 3 | 1 | 101 | 5 | ≤0.001 | 0/047 |
Sotiriadis et al. | 94 | 5 | 0 | 193 | 5 | 99 | 3 | 0 | 201 | 3 | 0/88 | 0/014 |
Mohammad et al. [21] | 25 | 10 | 0 | 60 | 10 | 41 | 4 | 0 | 86 | 4 | 0/75 | 0/044 |
Altintas et al. [41] | 105 | 9 | 0 | 219 | 9 | 172 | 13 | 0 | 357 | 13 | 0/62 | 0/035 |
Toth et al. [42] | 138 | 13 | 0 | 289 | 13 | 145 | 12 | 0 | 302 | 12 | 0/61 | 0/038 |
Pasquier et al. | 296 | 15 | 0 | 607 | 15 | 574 | 25 | 0 | 1173 | 25 | 0/6 | 0/02 |
Biswas et al. [43] | 83 | 2 | 0 | 168 | 2 | 31 | 0 | 0 | 62 | 0 | ≤0.001 | 0 |
Lvanov et al. | 133 | 19 | 1 | 285 | 21 | 93 | 7 | 0 | 193 | 7 | 0/71 | 0/035 |
Mukhopadhyay et al. [44] | 80 | 4 | 0 | 164 | 4 | 80 | 0 | 0 | 160 | 0 | ≤0.001 | 0 |
Ciacci et al. [45] | 38 | 1 | 0 | 77 | 1 | 70 | 2 | 0 | 142 | 2 | 0/9 | 0/013 |
Mohamed et al. [46] | 6 | 12 | 2 | 24 | 16 | 19 | 1 | 0 | 39 | 1 | 0/9 | 0/025 |
Hussein et al. [47] | 104 | 36 | 5 | 244 | 46 | 181 | 24 | 0 | 386 | 24 | 0/37 | 0/058 |
Serrano et al. [17] | 95 | 5 | 0 | 195 | 5 | 95 | 5 | 0 | 195 | 5 | 0/79 | 0/025 |
Settin et al. | 54 | 17 | 1 | 125 | 19 | 69 | 1 | 0 | 139 | 1 | 0/95 | 0/007 |
Dissanayake et al. [32] | 196 | 4 | 0 | 396 | 4 | 195 | 5 | 0 | 395 | 5 | 0/85 | 0/012 |
Gazi et al. | 50 | 6 | 1 | 106 | 8 | 43 | 4 | 0 | 90 | 4 | 0/76 | 0/042 |
Karata et al. | 66 | 16 | 2 | 148 | 20 | 66 | 18 | 0 | 150 | 18 | 0/27 | 0/107 |
Mierla et al. [48] | 260 | 21 | 2 | 541 | 25 | 95 | 5 | 0 | 195 | 5 | 0/79 | 0/025 |
Ozdemir et al. [49] | 433 | 109 | 1 | 975 | 111 | 104 | 2 | 0 | 210 | 2 | 0/92 | 0/009 |
Torabi et al. [50] | 87 | 12 | 1 | 186 | 14 | 96 | 4 | 0 | 196 | 4 | 0/83 | 0/02 |
Kaur et al. | 102 | 4 | 1 | 208 | 6 | 573 | 15 | 0 | 1161 | 15 | 0/75 | 0/012 |
Parveen et al. | 950 | 50 | 0 | 1950 | 50 | 488 | 12 | 0 | 988 | 12 | 0/78 | 0/012 |
Ardestani et al. | 78 | 2 | 0 | 158 | 2 | 79 | 1 | 0 | 159 | 1 | 0/95 | 0/006 |
Cardona et al. [51] | 92 | 1 | 0 | 185 | 1 | 205 | 1 | 0 | 411 | 1 | 0/97 | 0/002 |
Kazerooni et al. [52] | 43 | 12 | 5 | 98 | 22 | 54 | 4 | 2 | 112 | 8 | 0.48 | 0.734 |
Baumann et al. | 592 | 49 | 0 | 1233 | 49 | 145 | 12 | 0 | 302 | 12 | 0/61 | 0/038 |
Parand et al. [53] | 72 | 15 | 3 | 159 | 21 | 38 | 6 | 0 | 82 | 6 | 0/62 | 0/068 |
Zonouzi et al. [54] | 87 | 2 | 0 | 176 | 2 | 50 | 0 | 0 | 100 | 0 | ≤0.001 | 0 |
Dutra et al. | 142 | 3 | 0 | 287 | 3 | 131 | 4 | 0 | 266 | 4 | 0/86 | 0/014 |
Isaoglu et al. | 47 | 13 | 0 | 107 | 13 | 39 | 1 | 0 | 79 | 1 | 0/93 | 0/012 |
Pietropolli et al. [55] | 168 | 18 | 0 | 354 | 18 | 125 | 4 | 0 | 254 | 4 | 0/85 | 0/015 |
Lino et al. | 79 | 4 | 0 | 162 | 4 | 96 | 2 | 0 | 194 | 2 | 0/91 | 0/01 |
Sharma et al. [56] | 36 | 40 | 2 | 112 | 44 | 77 | 1 | 0 | 155 | 1 | 0/95 | 0/006 |
Farahmand et al. | 302 | 28 | 0 | 632 | 28 | 340 | 10 | 0 | 690 | 10 | 0/78 | 0/014 |
Kashif et al. [57] | 53 | 3 | 0 | 109 | 3 | 56 | 0 | 0 | 112 | 0 | ≤0.001 | 0 |
Gonçalves et al. [58] | 133 | 4 | 0 | 270 | 4 | 98 | 2 | 0 | 198 | 2 | 0/91 | 0/01 |
Khaniani et al. [59] | 202 | 8 | 0 | 412 | 8 | 158 | 2 | 0 | 318 | 2 | 0/93 | 0/006 |
Eldeen et al. | 0 | 72 | 24 | 72 | 120 | 0 | 94 | 2 | 94 | 98 | ≤0.001 | 0/51 |
Wolski et al. [60] | 333 | 26 | 0 | 692 | 26 | 378 | 21 | 1 | 777 | 23 | 0/23 | 0/028 |
Elgari et al. [61] | 56 | 4 | 0 | 116 | 4 | 74 | 6 | 0 | 154 | 6 | 0/72 | 0/037 |
Mahmutbegović et al. [62] | 44 | 7 | 0 | 95 | 7 | 142 | 12 | 0 | 296 | 12 | 0/61 | 0/038 |
Wingeyer et al. | 239 | 8 | 0 | 486 | 8 | 105 | 2 | 0 | 212 | 2 | 0/92 | 0/009 |
Jusić et al. | 51 | 9 | 0 | 111 | 9 | 77 | 3 | 0 | 157 | 3 | 0/86 | 0/018 |
Taghi Kardi et al. | 236 | 12 | 2 | 484 | 16 | 109 | 5 | 2 | 223 | 9 | ≤0.001 | 0/038 |
Xu et al. | 426 | 0 | 0 | 852 | 0 | 443 | 1 | 0 | 887 | 1 | 0/98 | 0/001 |
Bigdeli et al. [63] | 150 | 30 | 20 | 330 | 70 | 192 | 8 | 0 | 392 | 8 | 0/77 | 0/02 |
Yengel et al. | 130 | 1 | 14 | 261 | 29 | 102 | 0 | 3 | 204 | 6 | 0/65 | 0/394 |