Skip to main content
Fig. 5 | Thrombosis Journal

Fig. 5

From: Collagen-dependent platelet dysfunction and its relevance to either mitochondrial ROS or cytosolic superoxide generation: a question about the quality and functional competence of long-stored platelets

Fig. 5

Collagen induced platelet aggregation and its correlation with ROS generation in stored platelets. a shows the representative images of platelet aggregation curve in response to collagen on day0 and 5 of storage. Graph b demonstrates platelet aggregations during storage. A direct correlation was found between collagen-dependent platelet aggregation and either mitochondrial ROS (r = − 0.81; p < 0.001) or cytosolic superoxide generation (r = − 0.85; p < 0.001) (graph c). Correlations were analyzed by Spearman’s rank correlation test. P values of less than 0.05 were considered to be significant. Correlation graphs have been plotted using accumulating data obtained during storage from day 0 to day 5. ***p < 0.001, **p < 0.01, *p < 0.05, ns: not significant p > 0.05 (n = 6)

Back to article page

Thrombosis Journal

ISSN: 1477-9560

Contact us