Prevalence of venous obstructions in (recurrent) venous thromboembolism: a case-control study

Thrombosis Journal

Table 4 Long-term treatment outcomes

	Recurrent VTE N = 32	No recurrent VTE N = 24	Total N = 56	Odds ratio (95% CI)
Villalta score [15]	5.55 ± 3.02	5.26 ± 2.63	5.43 ± 2.84	–
- Subjective score	1.63 ± 1.43	2.22 ± 2.30	1.87 ± 1.85	–
- Objective score	4.03 ± 3.07	3.08 ± 1.74	3.62 ± 2.60	–
Post-Thrombotic syndrome^a [15, 17]	20 (62.5)	14 (58.3)	34 (60.7)	1.19 (0.40–3.51)
- None (0–4)	11 (34.4)	9 (37.5)	20 (35.7)	0.87 (0.29–2.63)
- Mild (5–9)	17 (53.1)	11 (45.8)	28 (50.0)	1.34 (0.46–3.87)
- Moderate (10–14)	3 (9.4)	3 (12.5)	6 (10.7)	0.72 (0.13–3.95)
- Severe (≥15 or venous ulceration)	0 (0.0)	0 (0.0)	0 (0.0)	0.75 (0.01–39.3)
- Missing	1 (3.1)	1 (4.2)	2 (3.6)	0.74 (0.04–12.5)
SF-36^b − Reported health transition	51.7 ± 18.5	52.1 ± 14.6	51.9 ± 16.7	–
VEINES QOL/Sym^c	49.5 ± 11.1	51.5 ± 8.2	50.4 ± 9.9	–
VEINES QOL/Sym, intrinsic score^d	71.3 ± 14.8	72.4 ± 12.2	71.8 ± 13.6	–

Data are n (%) or mean ± SD
None of the variables mentioned in this table showed statistical significant difference between groups
VTE Venous thrombo-embolism
^a Post-thrombotic syndrome was defined according to the definition stated by the International Society of Thrombosis and Haemostasis. This definition requires a single Villalta-score ≥ 5 assessed at 6 months or more after the acute venous thrombo-embolic event [17]
^bThe SF-36 is a questionnaire aimed at the generic health-related quality of life as reported by the patients. It comprises 36 questions covering 8 different health-related dimensions: Physical functioning, Role limitations due to physical health, Role limitations due to emotional health, Energy/Fatigue, Emotional well-being, Social functioning, Bodily pain, and General health perceptions [18]
^cThe VEINES QOL/SYM is a questionnaire addressing the disease-specific self-reported quality of life in DVT patients. It entails 25 questions regarding the limitations, symptoms, and changes encountered as a result of the acute thromboembolic event. The final summarizing score is adapted to the study population [19, 20]
^dBy using the method by Bland et al. [21] the VEINES QOL/SYM summarizing score can be transformed into an intrinsic score which allows comparison to other quality of life scores

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