Autopsy and statistical evidence of disturbed hemostasis progress in COVID-19: medical records from 407 patients

Thrombosis Journal

Table 1 Demographic and clinical characteristics and laboratory indices of 9 autopsy cases

Case	1	2	3	4	5	6	7	8	9	Median (IQR)
Age - years	70	66	53	83	80	62	51	78	67	67 (63–78)
Gender	Male	Female	Female	Male	Female	Male	Male	Female	Male
Hospital stay - days	20	10	22	29	5	15	5	12	22	15 (10–22)
Comorbidities	Cerebral infarction, hypertension	Hypertension	Hypertension	Cerebral infarction, hypertension	Hypertension, coronary heart disease, renal dysfunction, lacunar infarction, slow to emphysema	NA	Hypertension (level 3 with very high risk), gout	Hypertension, coronary artery disease	NA
Hyaline thrombus distribution of major organs^a
Lung	√	√	√	√	√	√	√	√	√
Kidney		√							√
Heart				√
Brain	√	√	√		√
Spleen	√	√	√		√
Laboratory findings of coagulation relevant indices^b
PLT - × 10⁹/L	63	127	116	134	76	167	161	66	174	161.0 (134.0–167.0)
PT - s	19.2	13.5	13	12	14.5	13.7	126.2	19.3	12	12.5 (12.0–13.1)
APTT - s	45.2	27.9	23.4	35.1	46.3	41.9	83.5	41.6	35.1	31.5 (26.8–35.1)
TT - s	65.2	14.9	16.7	16.2	18.2	16.7	27.8	NA	16.2	16.5 (16.2–16.7)
FIB - g/L	12.73	45.43	18.76	3.36	1.3	1.3	15.94	77.33	3.36	1.3 (1.3–2.3)
D-dimer - μg/mL	1.5	6.2	2.2	3.6	6.1	3.6	3.6	NA	NA	3.6 (3.3–3.6)
DIC	6	5	5	5	5	4	5	6	5	5.0 (5.0–5.0)

^a Blank cells represent no obvious thrombi in those organs. ^b NA indicate the data are not available

ISSN: 1477-9560