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Table 3 Relations between DIC resolution and treatment outcome in DIC with infectious disease

From: Analysis of the association between resolution of disseminated intravascular coagulation (DIC) and treatment outcomes in post-marketing surveillance of thrombomodulin alpha for DIC with infectious disease and with hematological malignancy by organ failure

Group

OS, % (n)

κ

DIC resolution

DIC non-resolution

Point estimate

95% CI, [lower, upper] limits

SOFA score

 0–6

91.3 (84)

69.6 (48)

0.234 ± 0.067

[0.103, 0.366]

 7–12

89.7 (201)

58.5 (161)

0.295 ± 0.035

[0.226, 0.365]

 13–24

84.5 (71)

41.8 (107)

0.311 ± 0.043

[0.227, 0.394]

AT activity, %

  ≤ 30

77.1 (27)

38.8 (38)

0.301 ± 0.074

[0.156, 0.446]

 30 < AT activity ≤50

87.3 (117)

51.2 (134)

0.300 ± 0.039

[0.225, 0.376]

 50 < AT activity ≤70

90.9 (169)

53.4 (125)

0.353 ± 0.039

[0.277, 0.429]

  > 70

89.6 (112)

54.6 (83)

0.333 ± 0.049

[0.238, 0.428]

  1. The degree of accordance between DIC resolution and treatment outcome according to the SOFA score group was analyzed by κ coefficient in DIC with infectious disease
  2. CI confidence interval, DIC disseminated intravascular coagulation, OS overall survival, SOFA sequential organ failure assessment
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Thrombosis Journal

ISSN: 1477-9560

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