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Table 5 Relations between DIC resolution and treatment outcome in DIC with hematological malignancy

From: Analysis of the association between resolution of disseminated intravascular coagulation (DIC) and treatment outcomes in post-marketing surveillance of thrombomodulin alpha for DIC with infectious disease and with hematological malignancy by organ failure

Group

OS, % (n)

κ

DIC resolution

DIC non-resolution

Point estimate

95% CI, [lower, upper] limits

Total bilirubin, mg/L

  < 1.2

92.3 (240)

70.3 (104)

0.251 ± 0.046

[0.162, 0.340]

  ≥ 1.2

90.3 (56)

43.7 (38)

0.434 ± 0.066

[0.306, 0.563]

Creatinine, mg/dL

  < 1.2

92.1 (268)

66.5 (125)

0.283 ± 0.041

[0.203, 0.364]

  ≥ 1.2

87.2 (41)

41.7 (25)

0.437 ± 0.080

[0.279, 0.594]

LDH, U/L

  ≤ 222

96.2 (51)

69.6 (16)

0.322 ± 0.113

[0.102, 0.543]

  > 222

91.4 (255)

59.5 (131)

0.336 ± 0.039

[0.260, 0.412]

  1. The degree of accordance between DIC resolution and treatment outcome according to the total bilirubin level was analyzed by κ coefficient in DIC with hematological malignancy
  2. CI confidence interval, DIC disseminated intravascular coagulation, LDH lactate dehydrogenase, OS overall survival
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Thrombosis Journal

ISSN: 1477-9560

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