Table 2 Reproductive history of patients admitted to the study
From: Pregnancy complications in G20210A mutation carriers associated with high prothrombin activity
Clinical manifestation of prothrombin G20210A mutation | Study group n = 140 | Control group n = 150 | Statistics | |||
|---|---|---|---|---|---|---|
total | % | total | % | p | OR. 95%CI | |
Total number of pregnancies | 363 | – | 451 | – | > 0.05 | – |
Artificial abortion | 47 | 12.5 | 46 | 10.2 | 0.2 | 1.3 (0.9–1.9) |
Planned pregnancy | 316 | 87.1 | 406 | 90.0 | 0.2 | 0.97 (0.9–1.0) |
Reproductive losses up to 12 weeks | 92 | 9.1 | 47 | 11.6 | < 0.0001 | 2.5 (1.8–3.5) |
non-developing pregnancy | 53 | 16.8 | 11 | 2.4 | < 0.0001 | 6.2 (3.2–11.7) |
spontaneous miscarriage | 32 | 10.1 | 31 | 7.6 | 0.2 | 1.3 (0.8–2.1) |
ectopic pregnancy | 7 | 1.9 | 5 | 1.1 | 0.2 | 2.2 (0.7–7.6) |
Favorable pregnancy | 133 | 42 | 304 | 74.6 | < 0.0001 | 1.8 (1.5–2.0) |
Total number of deliveries | 207 | 65.5 | 359 | 88.4 | < 0.0001 | 1.3 (1.2–1.5) |
Preterm delivery | 30 | 9.5 | 6 | 1.5 | < 0.0001 | 6.4 (2.7–15.2) |
Fetal growth restriction | 21 | 6.6 | 16 | 3.9 | 0.1 | 1.7 (0.9–3.2) |
Preeclampsia | 26 | 8.2 | 13 | 3.2 | 0.004 | 2.6 (1.3–4.9) |
severe preeclampsia | 15 | 4.7 | 2 | 0.5 | 0.003 | 9.6 (2.2–41.8) |
Antenatal fetal death | 6 | 1.9 | 1 | 0.2 | 0.06 | 7.7 (0.9–63.7) |