Fig. 3
From: Calibrated automated thrombogram II: removing barriers for thrombin generation measurements
Dose-dependent effect of DOACs on thrombin generation. Plasma samples were spiked with dabigatran, apixaban or rivaroxaban (0–200 ng/ml) and thrombin generation was measured with CAT-I and CAT-II. Lag time (A,D), peak height (B,E), ETP (C, F) and time to peak (G,H) were determined in thrombin generation curves obtained with CAT-I and CAT-II methods