Prevalence, risk, and outcome of deep vein thrombosis in acute respiratory distress syndrome

Thrombosis Journal

Table 5 Independent Predictors of Deep Vein Thrombosis in Patients with Direct and Indirect Acute Respiratory Distress Syndrome

Characteristics	Total ARDS (N = 225)		Direct ARDS (N = 111)		Indirect ARDS (N = 114)		P Value for Interaction With ARDS Type
Characteristics	Adjusted OR (95% CI)	P value	Adjusted OR (95% CI)	P value	Adjusted OR (95% CI)	P value	P Value for Interaction With ARDS Type
Age (per 10 years)	1.422 (1.147–1.763)	0.001	1.504 (1.025–2.207)	0.037	1.410 (1.070–1.856)	0.015	0.030
Serum creatinine (per 10 μmol/L)	0.939 (0.908–0.970)	< 0.001	0.857 (0.789–0.930)	< 0.001	0.971 (0.936–1.008)	0.120	0.006
Procalcitonin (ng/mL)	1.033 (0.997–1.070)	0.071	1.035 (0.975–1.099)	0.264	1.035 (0.989–1.084)	0.134
D-dimer (μg/ml)	1.065 (0.985–1.151)	0.114	1.059 (0.852–1.317)	0.606	1.056 (0.971–1.149)	0.205
PaO₂/FiO₂	0.996 (0.990–1.002)	0.223	0.996 (0.986–1.006)	0.453	0.995 (0.987–1.004)	0.295
IMV	3.168 (1.579–6.356)	0.001	5.272 (1.536–18.100)	0.008	2.787 (1.144–6.792)	0.024

Multivariable logistic regression was performed in the overall ARDS cohort and then in the direct ARDS and indirect ARDS groups separately. The interactions of ARDS type (direct or indirect) with age, serum creatinine level, level of procalcitonin, level of D-dimer, PaO₂/FiO₂, and IMV were included in the regression analysis
Abbreviations: ARDS acute respiratory distress syndrome, CI confidence interval, DVT deep venous thrombosis, FiO₂ fraction of inspired oxygen, IMV invasive mechanical ventilation, OR odds ratio, PaO₂ partial pressure of arterial oxygen

ISSN: 1477-9560