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Table 5 Independent Predictors of Deep Vein Thrombosis in Patients with Direct and Indirect Acute Respiratory Distress Syndrome

From: Prevalence, risk, and outcome of deep vein thrombosis in acute respiratory distress syndrome

Characteristics Total ARDS (N = 225) Direct ARDS (N = 111) Indirect ARDS (N = 114) P Value for Interaction With ARDS Type
Adjusted OR (95% CI) P value Adjusted OR (95% CI) P value Adjusted OR (95% CI) P value
Age (per 10 years) 1.422 (1.147–1.763) 0.001 1.504 (1.025–2.207) 0.037 1.410 (1.070–1.856) 0.015 0.030
Serum creatinine (per 10 μmol/L) 0.939 (0.908–0.970) < 0.001 0.857 (0.789–0.930) < 0.001 0.971 (0.936–1.008) 0.120 0.006
Procalcitonin (ng/mL) 1.033 (0.997–1.070) 0.071 1.035 (0.975–1.099) 0.264 1.035 (0.989–1.084) 0.134  
D-dimer (μg/ml) 1.065 (0.985–1.151) 0.114 1.059 (0.852–1.317) 0.606 1.056 (0.971–1.149) 0.205  
PaO2/FiO2 0.996 (0.990–1.002) 0.223 0.996 (0.986–1.006) 0.453 0.995 (0.987–1.004) 0.295  
IMV 3.168 (1.579–6.356) 0.001 5.272 (1.536–18.100) 0.008 2.787 (1.144–6.792) 0.024  
  1. Multivariable logistic regression was performed in the overall ARDS cohort and then in the direct ARDS and indirect ARDS groups separately. The interactions of ARDS type (direct or indirect) with age, serum creatinine level, level of procalcitonin, level of D-dimer, PaO2/FiO2, and IMV were included in the regression analysis
  2. Abbreviations: ARDS acute respiratory distress syndrome, CI confidence interval, DVT deep venous thrombosis, FiO2 fraction of inspired oxygen, IMV invasive mechanical ventilation, OR odds ratio, PaO2 partial pressure of arterial oxygen