Fig. 3
Healthy individuals with one or more cardiovascular risk factors show augmented thrombogenicity. (a) The times to 10, 20, 30, 40, 50, and 60 kPa (at a shear rate of 1500 s− 1) in the T-TAS in healthy individuals with or without cardiovascular risk factor(s) are shown. Filled circles and error bars indicate medians and interquartile ranges, respectively. A nonlinear curve fit model was used for estimating theoretical flow pressure curves in individuals with or without cardiovascular risk factor(s). (b) The distribution of the AUC10 in the T-TAS in healthy individuals without (n = 28) or with one (n = 59), two (n = 26), or three (n = 9) cardiovascular risk factors is shown as violin plots. Bold and dotted horizontal lines indicate medians and quartiles, respectively. The correlation between the AUC10 (at a shear rate of 1500 s− 1) in the T-TAS and the number of cardiovascular risk factors was analyzed by Spearman’s rank correlation test