Table 2 The clinical and biochemical data according to PCSK9 levels

 Age (years)

55.62 ± 11.01

54.92 ± 11.12

56.32 ± 10.86

0.002

 Male sex n(%)

1387 (60.5)

795 (69.4)

592 (51.6)

< 0.001

 BMI (kg/m²)

25.63 ± 3.38

25.76 ± 3.39

25.49 ± 3.37

0.054

 CAD n(%)

1447 (63.1)

723 (63.1)

724 (63.1)

0.987

 DM n(%)

538 (23.5)

257 (22.4)

281 (24.5)

0.242

 Hypertension n(%)

1418 (61.8)

710 (62.0)

708 (61.7)

0.910

 Smoking n(%)

788 (34.4)

422 (36.8)

366 (31.9)

0.013

 Drinking n(%)

468 (20.4)

261 (22.8)

207

0.005

 Family history of CAD n(%)

514 (22.4)

236 (20.6)

278 (24.2)

0.036

 SBP (mmHg)

128.05 ± 18.01

128.58 ± 17.97

127.52 ± 18.04

0.161

 DBP (mmHg)

79.59 ± 11.19

80.08 ± 11.21

79.1 ± 11.16

0.035

 TC (mmol/L)

4.9 ± 1.09

4.68 ± 0.96

5.12 ± 1.17

< 0.001

 TG (mmol/L)

(1.15,2.3)

1.53 (1.11,2.23)

1.64 (1.19,2.35)

0.012

 HDL-C (mmol/L)

1.11 ± 0.35

1.09 ± 0.36

1.14 ± 0.33

0.001

 LDL-C (mmol/L)

3.2 ± 1

2.99 ± 0.88

3.41 ± 1.08

< 0.001

 Glu (mmol/L)

5.65 ± 1.88

5.6 ± 2.1

5.69 ± 1.64

0.264

 HbA1C (%)

6.02 ± 1.0

5.94 ± 0.94

6.09 ± 1.06

< 0.001

 hsCRP (mg/L)

1.37 (0.72,2.46)

1.32 (0.71,2.46)

1.47 (0.73,2.63)

0.009

 APTT (s)

36.25 ± 3.9

36.46 ± 3.86

36.03 ± 3.92

0.008

 PT (s)

12.75 ± 0.64

12.84 ± 0.63

12.67 ± 0.63

< 0.001

 PT-t (1/s)

0.83 (0.63.1.25)

0.77 (0.59,1.11)

0.83 (0.67,1.43)

< 0.001

 TT (s)

16.4 ± 1.25

16.38 ± 1.08

16.42 ± 1.39

0.386

 Fib (g/L)

3.06 ± 0.73

2.98 ± 0.64

3.15 ± 0.79

< 0.001

 D dimer (μg/mL)

0.31 (0.24,0.41)

0.3 (0.24,0.39)

0.32 (0.24,0.43)

0.011

 Platelet(10^12)

216.79 ± 55.66

211.32 ± 54.48

222.25 ± 56.31

< 0.001

 Aspirin/Clopidogrel n(%)

748 (32.6)

379 (33.1)

369 (32.2)

0.646

 ACEI/ARB n(%)

383 (16.7)

193 (16.8)

190 (16.6)

0.859