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Table 1 Baseline characteristics

From: Association between obstructive sleep apnea and venous thromboembolism recurrence: results from a French cohort

Variables Total Non-OSA patients OSA patients p-value
Age (years) Mean (SD) 56.75 (19.4) 56.53 (19.6) 62.67 (13.3) 0.008
Age (years) n (%)     0.002
  ≤ 50 805 (38.2) 790 (38.8) 15 (20.3)  
  50–65 464 (22.0) 439 (21.6) 25 (33.8)  
  >  65 839 (39.8) 805 (39.6) 34 (45.9)  
Gender Female n (%) 1177 (55.8) 1151 (56.6) 26 (35.1) < 0.001
BMI (kg/m2) Mean (SD) 26.27 (5.0) 26.10 (4.9) 30.90 (5.5) < 0.001
BMI (kg/m2) n (%)     < 0.001
  ≤ 25 917 (44.4) 908 (45.6) 9 (12.5)  
  >  25 - ≤ 30 763 (36.9) 735 (36.9) 28 (38.9)  
  >  30 - ≤ 35 268 (13.0) 252 (12.6) 16 (22.2)  
  >  35 117 (5.7) 98 (4.9) 19 (26.4)  
Smoking n (%) 973 (47.0) 936 (46.9) 37 (51.4) 0.53
Atrial fibrillation n (%) 58 (2.8) 55 (2.8) 3 (4.2) 0.71
Chronic heart failure: n (%): n (%) 134 (6.4) 125 (6.1) 9 (12.2) 0.07
Kidney failure n (%) 83 (3.9) 73 (3.6) 10 (13.5) < 0.001
Stroke n (%) 68 (3.2) 55 (2.7) 13 (17.6) < 0.001
Characteristics of index VTE n (%)     0.032
  Isolated PE 558 (26.5) 530 (26.1) 28 (37.8)  
  PE associated with DVT 610 (29.0) 587 (28.9) 23 (31.1)  
  Isolated DVT 934 (44.4) 911 (44.9) 23 (31.1)  
Characteristics of recurrent VTE n (%)     0.23
  Isolated PE 63 (25.0) 61 (25.1) 2 (22.2)  
  PE associated with proximal DVT 44 (17.5) 40 (16.5) 4 (44.4)  
  PE associated with distal DVT 20 (7.9) 19 (7.8) 1 (11.1)  
  Isolated proximal DVT 84 (33.3) 83 (34.2) 1 (11.1)  
  Isolated distal DVT 41 (16.3) 40 (16.5) 1 (11.1)  
Anticoagulant duration n (%)     0.37
  ≤ 90 days 190 (9.0) 184 (9.1) 6 (8.1)  
  >  90 - ≤ 180 days 543 (25.8) 527 (25.9) 16 (21.6)  
  >  180 - ≤ 360 days 895 (42.5) 866 (42.6) 29 (39.2)  
  >  360 days 478 (22.7) 455 (22.4) 23 (31.1)  
Unprovoked VTE n (%) 1199 (56.9) 1148 (56.4) 51 (68.9) 0.044
Provoked VTE n (%) 910 (43.1) 887 (43.6) 23 (31.1)  
Aspirin n (%) 215 (10.2) 203 (10.0) 12 (16.2) 0.12
Statin n (%) 192 (9.1) 181 (8.9) 11 (14.9) 0.12
CPAP n (%) 63 (69.2) 0 (0.0) 63 (85.1) < 0.001
OSA history n (%) 46 (2.2) 0 (0.0) 46 (2.2)  
OSA occurrence n (%) 28 (1.3) 0 (0.0) 28 (1.3)  
PSG or HST n (%)    17 (0.8) 57 (77.0)  
  Mean (SD)     
  Total number of apneas 88.50 (105.4) 15.64 (22.6) 114.00 (111.2) 0.002
  Number of apneas by hours 11.92 (14.4) 1.81 (2.9) 15.37 (15.2) 0.002
  Number of obstructive apneas 59.58 (80.8) 6.93 (11.1) 78.97 (86.7) 0.003
  Number of central apneas 6.40 (17.5) 1.93 (4.9) 8.05 (20.1) 0.27
  Number of mixed apneas 8.92 (19.8) 1.21 (2.2) 11.76 (22.6) 0.09
  Apnea hypopnea index by hour 31.82 (20.8) 8.15 (4.3) 38.88 (18.4) < 0.001
Nocturnal Desaturation    17 (0.8) 57 (77.0)  
  Mean (SD)     
  Percentage of time < 90% 29.73 (31.3) 21.41 (32.4) 32.51 (30.7) 0.24
  Percentage of time < 85% 11.26 (22.1) 8.71 (23.0) 12.08 (22.0) 0.63
  Percentage of time < 80% 3.35 (12.1) 0.08 (0.3) 4.42 (13.8) 0.27
  1. BMI body mass index, CPAP continuous positive airway pressure, OSA Obstructive Sleep Apnea, PSG polysomnography, HST Home Sleep Tests, VTE Venous Thromboembolism