Table 1 Baseline characteristics
Variables | Total | Non-OSA patients | OSA patients | p-value | |
|---|---|---|---|---|---|
Age (years) | Mean (SD) | 56.75 (19.4) | 56.53 (19.6) | 62.67 (13.3) | 0.008 |
Age (years) | n (%) | 0.002 | |||
≤ 50 | 805 (38.2) | 790 (38.8) | 15 (20.3) | ||
50–65 | 464 (22.0) | 439 (21.6) | 25 (33.8) | ||
> 65 | 839 (39.8) | 805 (39.6) | 34 (45.9) | ||
Gender | Female n (%) | 1177 (55.8) | 1151 (56.6) | 26 (35.1) | < 0.001 |
BMI (kg/m2) | Mean (SD) | 26.27 (5.0) | 26.10 (4.9) | 30.90 (5.5) | < 0.001 |
BMI (kg/m2) | n (%) | < 0.001 | |||
≤ 25 | 917 (44.4) | 908 (45.6) | 9 (12.5) | ||
> 25 - ≤ 30 | 763 (36.9) | 735 (36.9) | 28 (38.9) | ||
> 30 - ≤ 35 | 268 (13.0) | 252 (12.6) | 16 (22.2) | ||
> 35 | 117 (5.7) | 98 (4.9) | 19 (26.4) | ||
Smoking | n (%) | 973 (47.0) | 936 (46.9) | 37 (51.4) | 0.53 |
Atrial fibrillation | n (%) | 58 (2.8) | 55 (2.8) | 3 (4.2) | 0.71 |
Chronic heart failure: n (%): | n (%) | 134 (6.4) | 125 (6.1) | 9 (12.2) | 0.07 |
Kidney failure | n (%) | 83 (3.9) | 73 (3.6) | 10 (13.5) | < 0.001 |
Stroke | n (%) | 68 (3.2) | 55 (2.7) | 13 (17.6) | < 0.001 |
Characteristics of index VTE | n (%) | 0.032 | |||
Isolated PE | 558 (26.5) | 530 (26.1) | 28 (37.8) | ||
PE associated with DVT | 610 (29.0) | 587 (28.9) | 23 (31.1) | ||
Isolated DVT | 934 (44.4) | 911 (44.9) | 23 (31.1) | ||
Characteristics of recurrent VTE | n (%) | 0.23 | |||
Isolated PE | 63 (25.0) | 61 (25.1) | 2 (22.2) | ||
PE associated with proximal DVT | 44 (17.5) | 40 (16.5) | 4 (44.4) | ||
PE associated with distal DVT | 20 (7.9) | 19 (7.8) | 1 (11.1) | ||
Isolated proximal DVT | 84 (33.3) | 83 (34.2) | 1 (11.1) | ||
Isolated distal DVT | 41 (16.3) | 40 (16.5) | 1 (11.1) | ||
Anticoagulant duration | n (%) | 0.37 | |||
≤ 90 days | 190 (9.0) | 184 (9.1) | 6 (8.1) | ||
> 90 - ≤ 180 days | 543 (25.8) | 527 (25.9) | 16 (21.6) | ||
> 180 - ≤ 360 days | 895 (42.5) | 866 (42.6) | 29 (39.2) | ||
> 360 days | 478 (22.7) | 455 (22.4) | 23 (31.1) | ||
Unprovoked VTE | n (%) | 1199 (56.9) | 1148 (56.4) | 51 (68.9) | 0.044 |
Provoked VTE | n (%) | 910 (43.1) | 887 (43.6) | 23 (31.1) | |
Aspirin | n (%) | 215 (10.2) | 203 (10.0) | 12 (16.2) | 0.12 |
Statin | n (%) | 192 (9.1) | 181 (8.9) | 11 (14.9) | 0.12 |
CPAP | n (%) | 63 (69.2) | 0 (0.0) | 63 (85.1) | < 0.001 |
OSA history | n (%) | 46 (2.2) | 0 (0.0) | 46 (2.2) | |
OSA occurrence | n (%) | 28 (1.3) | 0 (0.0) | 28 (1.3) | |
PSG or HST n (%) | 17 (0.8) | 57 (77.0) | |||
Mean (SD) | |||||
Total number of apneas | 88.50 (105.4) | 15.64 (22.6) | 114.00 (111.2) | 0.002 | |
Number of apneas by hours | 11.92 (14.4) | 1.81 (2.9) | 15.37 (15.2) | 0.002 | |
Number of obstructive apneas | 59.58 (80.8) | 6.93 (11.1) | 78.97 (86.7) | 0.003 | |
Number of central apneas | 6.40 (17.5) | 1.93 (4.9) | 8.05 (20.1) | 0.27 | |
Number of mixed apneas | 8.92 (19.8) | 1.21 (2.2) | 11.76 (22.6) | 0.09 | |
Apnea hypopnea index by hour | 31.82 (20.8) | 8.15 (4.3) | 38.88 (18.4) | < 0.001 | |
Nocturnal Desaturation | 17 (0.8) | 57 (77.0) | |||
Mean (SD) | |||||
Percentage of time < 90% | 29.73 (31.3) | 21.41 (32.4) | 32.51 (30.7) | 0.24 | |
Percentage of time < 85% | 11.26 (22.1) | 8.71 (23.0) | 12.08 (22.0) | 0.63 | |
Percentage of time < 80% | 3.35 (12.1) | 0.08 (0.3) | 4.42 (13.8) | 0.27 | |