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Fig. 5 | Thrombosis Journal

Fig. 5

From: Thrombin generation capacity is enhanced by low antithrombin activity and depends on the activity of the related coagulation factors

Fig. 5

Effect of changes in coagulation factor activity on thrombin generation. This test is conducted at 30% and 50% AT activity. The adjustment method for each sample is as shown in the table above. Relative Values (%) = 100 × Parameters for each sample / The peak height value of the sample with PT 100%. A: Effect of changes in coagulation factor activity on thrombin generation at 30% AT activities. B: Effect of changes in coagulation factor activity on thrombin generation at 50% AT activities. PT% values 40% and 33% samples required the addition of an AT concentrate since it is not possible to mix and adjust the three samples while keeping the AT activity at 50%. PT% values 40% and 33% samples were adjusted by adding a small amount of recombinant AT concentrate and titrating to 50% AT. AT: antithrombin, PT: prothrombin time.

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Thrombosis Journal

ISSN: 1477-9560

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