Table 3 Demographics, presentation, the type of anticoagulant drugs and the presence of Addison disease in current cases and literature reviews of AH due to DOACs usage. NM = not mentioned, APLS = antiphospholipid syndrome, IJVT=internal jugular vein thrombosis, AH = adrenal hemorrhage, AI = adrenal insufficiency
No | Author, [reference] | Age/Gender | Presentation | Anticoagulant drugs | Anticoagulant drugs dosage | Reason to get Anticoagulant prophylaxis | Laterality of AH | Presence of Addison Disease as a medical background | AI secondary to the AH |
|---|---|---|---|---|---|---|---|---|---|
1 | W. Comuth(2017) [36] | 63/Female | Abdominal pain | Rivaroxaban (Xarelto) | 20 mg daily | APLS | Bilateral | - |  +  |
2 | Z. Sanford(2019) [22] | 42/Male | Acute onset severe right flank pain | Apixaban (Eliquis) | NM | APLS | Unilateral | - | - |
3 | B. A. Ly(2019) [37] | 61/Male | Nausea and vomiting | Rivaroxaban | 10Â mg daily | Knee Surgery | Unilateral | - | - |
4 | M. Alidoost(2019) [10] | 68/Female | Severe acute onset abdominal pain | Rivaroxaban | 10 mg daily | Knee Surgery | Bilateral | - |  +  |
5 | M. A. Arosemena(2020) [35] | 46 / Male | Syncopal episode | Rivaroxaban | NM | APLS | Bilateral | - |  +  |
6 | Current Case(2022) | 35/Female | Nausea and vomiting and buccal hyperpigmentation | Apixaban | 2.5 mg twice a day | IJVT | Unilateral |  +  |  +  |
7 | Current Case(2022) | 89/Female | Fatigue and loss of appetite | Rivaroxaban | 10 mg daily | Femur Surgery | Bilateral | - |  +  |