Fig. 5

Target relation between miR-92a-3p and Hmgcr. A The existence of binding sites of miR-92a-3p and Hmgcr; B Effect of miR-92a-3p on luciferase of Wt-Hmgcr and Mut-Hmgcr reporters; C Hmgcr enrichment under Ago2; D Effect of miR-92a-3p on Hmgcr protein expression in EPCs; * P < 0.05. In vitro experiments were undertaken on 3 biological and 3 technical replicates, and in vivo experiments were undertaken on n = 5 animals per group