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Table 3 Factors associated with poor anticoagulation and other secondary outcomes in long term care in Africa

From: Anticoagulation control, outcomes, and associated factors in long-term-care patients receiving warfarin in Africa: a systematic review

Authors’ name

Factors associated with poor anticoagulation outcomes (low TTR%)

Factors associated with bleeding events

Factors associated with Thromboembolism events

Factors associated with hospitalization events

Factors associated with mortality during warfarin therapy

Karuri et al., 2019 [36]

CHF, renal dysfunction

NA

NA

NA

NA

Sana et al., 2020 [43]

CHF, and nonvalvular AF type

Hypertension and antiplatelet use

obstructive sleep apnea and higher CHA2DS2VASc score

NA

CHF, and hypertension

Prinsloo et al., 2021 [38]

Patents aged < 50, hospitalization

NA

NA

NA

NA

Ahmed et al., 2017 [41]

Absence of pharmacists’ intervention

NA

NA

clinical pharmacy intervention (-)

NA

Botsile et al., 2020 [39]

NA

Duration of warfarin use, Increased level of education

NA

NA

NA

Masresha et al., 2021 [31]

potential medication interaction, presence of co-morbid conditions

NA

NA

NA

NA

Kizito et al., 2016 [47]

female gender, lower education level

NA

NA

NA

NA

Yimer et al., 2021 [40]

Receiving > 2 drugs with warfarin, heart failure comorbidity

NA

NA

NA

NA

Rejeb et al., 2019 [29]

NA

Poor TTR (< 50%)

NA

NA

NA

Mwita et al.,2017 [30]

Smoking and pulmonary hypertension

NA

NA

NA

NA

Ebrahim et al., 2018 [7]

Frequent INR monitoring

NA

NA

NA

NA

  1. CHF heart failure, NA Not applicable, TTR Time in therapeutic range, AF Atrial fibrillation, INR International normalized ratio