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Table 3 Unadjusted and adjusted odds ratio for early coagulopathy after OHCA

From: Early coagulopathy after pediatric out-of-hospital cardiac arrest: secondary analysis of a randomized clinical trial

Variables

Unadjusted ORs (95% CI)

P Value

Adjusted ORs (95% CI)

P Value

Age, years

0.88 [0.83, 0.93]

 < 0.001

0.89 [0.83, 0.95]

0.001

Primary etiology of cardiac arrest

 Cardiac

1 [Reference]

 

1 [Reference]

 

 Respiratory

2.91 [1.09, 9.23]

0.046

1.55 [0.48, 5.76]

0.481

 Other

3.84 [0.83, 19.54]

0.090

4.87 [0.82, 31.84]

0.086

 Unknown

3.47 [1.01, 13.36]

0.056

1.76 [0.41, 8.17]

0.451

Cardiac arrest witnessed

0.58 [0.33, 1.02]

0.061

NA

 

Duration of chest compression

  ≤ 15 min

1 [Reference]

 

1 [Reference]

 

  > 15 to ≤ 30 min

1.35 [0.63, 2.99]

0.449

0.89 [0.37, 2.17]

0.792

  > 30 min

4.61 [2.21, 10.05]

 < 0.001

2.87 [1.24, 6.83]

0.015

 Unable to determine

2.50 [0.61, 10.35]

0.195

1.69 [0.34, 8.33]

0.512

Doses of epinephrine

 ≤ 2

1 [Reference]

 

NA

 

  > 2 to ≤ 4

2.09 [1.05, 4.21]

0.038

NA

 

  > 4

4.51 [2.24, 9.33]

 < 0.001

NA

 

 Missing

6.05 [2.14, 18.97]

0.001

NA

 

Temperature upon admission, ℃

0.69 [0.59, 0.79]

 < 0.001

0.78 [0.66, 0.91]

0.002

Hypotension upon admission

1.77 [0.93, 3.41]

0.086

1.83 [0.81, 4.22]

0.148

WBC upon admission, 10^9/L

1.05 [1.02, 1.08]

0.002

1.04 [1.01, 1.08]

0.022

Hemoglobin upon admission, g/dL

0.89 [0.79, 0.98]

0.026

NA

 
  1. NA Not applicable, OHCA Out-of-hospital cardiac arrest, OR Odds ratio, WBC White blood cell