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Table 7 Analysis of differences in laboratory parameters and outcomes among PAI-1 genotypes

From: Clinical impact of the PAI-1 4G/5G polymorphism in Chinese patients with venous thromboembolism

Variables

5G/5G (n = 8)

4G/5G (n = 13)

4G/4G (n = 20)

P value

(4G/5G vs 5G/5G)

P value

(4G/4G vs 5G/5G)

P value

(4G/4G vs 4G/5G + 5G/5G)

Age, Mean ± SD

55.88 ± 17.92

50.85 ± 15.44

56.95 ± 19.65

0.522

0.891

0.462

Sex, n (%)

   

0.646

1

0.44

F

4 (50)

4 (31)

11 (55)

   

M

4 (50)

9 (69)

9 (45)

   

RBC, × 1012/L, Mean ± SD

3.98 ± 1.46

4.63 ± 0.49

4.07 (3.79, 4.4)

0.255

0.195

0.246

Hb, g/L, Mean ± SD

113.38 ± 26.81

140.31 ± 11.39

123.25 ± 20.58

0.026

0.37

0.319

HCT, %, Mean ± SD

34.4 ± 8.44

40.9 ± 3.61

36.62 ± 5.55

0.07

0.508

0.349

WBC, × 109/L, Median (IQR)

8.52 (5.68, 14.02)

6.85 (5.94, 8.93)

5.66 (4.97, 8.18)

0.547

0.136

0.1

L, × 109/L, Mean ± SD

1.47 ± 0.57

1.58 ± 0.56

1.49 ± 0.63

0.686

0.95

0.791

N, × 109/L, Median (IQR)

6.46 (3.35, 11.79)

4.93 (3.98, 5.51)

3.87 (3.04, 5.46)

0.595

0.213

0.148

PLT, × 109/L, Mean ± SD

232 ± 134.89

245.31 ± 89.42

212.4 ± 77.75

0.809

0.708

0.342

NLR, Median (IQR)

4.36 (2.36, 9.49)

2.76 (2.1, 3.84)

2.4 (2.03, 3.59)

0.414

0.258

0.372

PLR, Mean ± SD

149.62 ± 50.29

167.93 ± 61.06

133.88 (104.09, 203.83)

0.466

0.98

0.494

PT, s, Median (IQR)

12.15 (11.07, 12.85)

12 (11.5, 13.1)

12.35 (11.78, 14.75)

0.717

0.333

0.309

Fbg, g/L, Median (IQR)

3.36 (3.01, 3.99)

3.4 (2.7, 3.78)

2.97 (2.62, 3.87)

0.514

0.373

0.397

APTT, s, Median (IQR)

26.5 (25.55, 29.65)

28.9 (27.3, 29.6)

28.52 ± 3.94

0.328

0.722

0.62

TT, s, Mean ± SD

18 ± 2.07

17.83 ± 1.11

17.46 ± 1.11

0.835

0.502

0.308

D-dimer, μg/ml, Median (IQR)

2.56 (0.71, 9.89)

1.15 (0.57, 4.09)

1.3 (0.6, 3.12)

0.697

0.492

0.725

Outcome, n (%)

   

0.155

0.031

0.074

No recanalization

2 (25)

1 (8)

6 (30)

   

Partial recanalization

1 (12)

7 (54)

11 (55)

   

Complete recanalization

5 (62)

5 (38)

3 (15)

   
  1. RBC Red blood cell counts, Hb Hemoglobin, HCT Hematocrit, WBC White blood cell counts, L Lymphocyte counts, N Neutrophil counts, PLT Platelet counts, NLR Neutrophil-to-lymphocyte ratio, PLR Platelet-to-lymphocyte ratio, PT Prothrombin time, APTT Activated partial thromboplastin time, TT Thrombin time, Fbg Fibrinogen, IQR Interquartile range, SD Standard deviation
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Thrombosis Journal

ISSN: 1477-9560

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