Table 1 Baseline characteristics according to the liver fibrosis status staged by APRI
Liver fibrosis | Low | Intermediate | High | p Value |
|---|---|---|---|---|
Clinical characteristics | ||||
Age | 58.7 (10.3) | 57.6 (10.6) | 58.1 (10.7) | 0.028 |
Male | 4235 (75.1) | 542 (82.6) | 70 (76.9) | < 0.001 |
BMI | 25.9 (3.3) | 25.7 (3.2) | 26.1 (2.6) | 0.29 |
Diabetes mellitus | 1700 (30.1) | 176 (26.8) | 22 (24.2) | 0.108 |
Hypertension | 3680 (65.3) | 390 (59.5) | 55 (60.4) | 0.009 |
Hyperlipidemia | 3800 (67.4) | 409 (62.3) | 56 (61.5) | 0.019 |
Smoking | 3267 (57.9) | 407 (62.0) | 52 (57.1) | 0.127 |
Prior PCI | 1310 (23.2) | 161 (24.5) | 30 (33.0) | 0.076 |
Prior CABG | 225 (4.0) | 24 (3.7) | 4 (4.4) | 0.898 |
Prior MI | 772 (13.7) | 84 (12.8) | 9 (9.9) | 0.485 |
Prior cerebrovascular disease | 635 (11.3) | 74 (11.3) | 10 (11.0) | 0.997 |
Peripheral vascular disease | 154 (2.7) | 18 (2.7) | 2 (2.2) | 0.953 |
STEMI | 1139 (20.2) | 277 (42.2) | 58 (63.7) | < 0.001 |
NSTEMI | 357 (6.3) | 84 (12.8) | 8 (8.8) | < 0.001 |
UA | 4143 (73.5) | 295 (45.0) | 25 (27.5) | < 0.001 |
Left ventricular dysfunction | 269 (4.8) | 51 (7.8) | 19 (20.9) | < 0.001 |
Renal insufficiency | 2 (0.0) | 2 (0.3) | 0 (0.0) | 0.032 |
Procedural characteristics | ||||
Chronic total occlusion | 396 (7.0) | 24 (3.7) | 2 (2.2) | 0.001 |
Left main artery disease | 333 (5.9) | 37 (5.6) | 5 (5.5) | 0.952 |
Moderate to severe calcification | 850 (15.1) | 99 (15.1) | 14 (15.4) | 0.997 |
Lesion number | 1.4 (0.7) | 1.4 (0.7) | 1.4 (0.7) | 0.656 |
Lesion length | 28.1 (18.8) | 28.4 (17.2) | 26.7 (17.1) | 0.72 |
Minimum lesion diameter | 0.4 (0.5) | 0.3 (0.3) | 0.2 (0.3) | < 0.001 |
Drug-eluting stent | 5399 (95.7) | 618 (94.2) | 81 (89.0) | 0.002 |
Laboratory tests | ||||
AST, IU/L | 20.0 (7.4) | 56.1 (25.0) | 216.9 (167.1) | < 0.001 |
ALT, IU/L | 28.5 (19.3) | 71.9 (55.6) | 134.2 (142.8) | < 0.001 |
Albumin, g/dL | 42.6 (4.2) | 41.9 (4.7) | 40.7 (4.2) | < 0.001 |
Total bilirubin, μmol/L | 14.4 (5.4) | 15.7 (6.9) | 19.4 (10.5) | < 0.001 |
Triglycerides, mmol/L | 1.8 (1.1) | 1.8 (1.1) | 1.8 (0.8) | 0.499 |
Total cholesterol, mmol/L | 4.2 (1.1) | 4.2 (1.0) | 4.5 (0.8) | 0.043 |
LDL-C, mmol/L | 2.5 (0.9) | 2.5 (0.9) | 2.7 (0.8) | 0.075 |
HDL-C, mmol/L | 1.0 (0.3) | 1.0 (0.3) | 1.1 (0.3) | 0.04 |
Blood glucose, mmol/L | 6.3 (2.3) | 6.8 (3.0) | 8.2 (4.5) | < 0.001 |
High-sensitivity C-reactive protein, mg/L | 3.4 (3.9) | 5.3 (5.0) | 8.7 (5.8) | < 0.001 |