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Fig. 1 | Thrombosis Journal

Fig. 1

From: LINC00659 exacerbates endothelial progenitor cell dysfunction in deep vein thrombosis of the lower extremities by activating DNMT3A-mediated FGF1 promoter methylation

Fig. 1

LINC00659 is upregulated in IVC tissues and peripheral blood of patients with LEDVT A Volcano plot of differentially expressed lncRNAs in 6 human varicose vein tissues and 6 normal adjacent vein tissues in GSE51260 dataset. B RT-qPCR was applied to check LINC00659 level in the IVC tissues of patients with LEDVT (n = 15) and healthy controls (n = 15). C RT-qPCR detection of LINC00659 level in peripheral blood of patients with LEDVT (n = 15) and healthy controls (n = 15). D EPCs showed a cobblestone like morphology on day 3 after the first passage (n = 6), Scale bar = 25 μm. E Dual fluorescence labeling method of Dil-Ac-LDL/FITC-UAE-1 evaluation of the physiological behaviors of the EPCs (n = 4), Scale bar = 25 μm. F Immunofluorescence evaluation of CD34 and CD133 expression in EPCs (n = 4), Scale bar = 25 μm. G: RT-qPCR detection of LINC00659 level in EPCs isolated from patients with LEDVT and healthy controls (n = 6). Each experiment was repeated for 3 times. **P < 0.01, **P < 0.01 vs Control group

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Thrombosis Journal

ISSN: 1477-9560

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