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Fig. 7 | Thrombosis Journal

Fig. 7

From: LINC00659 exacerbates endothelial progenitor cell dysfunction in deep vein thrombosis of the lower extremities by activating DNMT3A-mediated FGF1 promoter methylation

Fig. 7

Knockdown of LINC00659 alleviates LEDVT in mice. A In vivo angiogenesis was assessed on day 7 after subcutaneous injection of LINC00659 shRNA lentivirus into mice (n = 10). B HE staining was applied to check IVC thrombosis pathological changes (n = 10). C The ratio of thrombus tissue weight to length in mice of each group (n = 10). D Leukocyte numbers in thrombi of mice in each group. E The level of LINC00659 in IVC was checked by RT-qPCR (n = 10). F–H The protein levels of EIF4A3 and FGF1 in IVC were tested by Western blotting (n = 10). *P < 0.05, **P < 0.01

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Thrombosis Journal

ISSN: 1477-9560

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