Fig. 4

Representative histological photos of endoscopic biopsy specimens taken from the stomach and colon (Hematoxylin–eosin staining, original magnification × 100). Before effective treatment, there was chronic inflammation, extensive interstitial edema, gland expansion and hyperplastic polyps in stomach were present (A), inflammatory cell infiltration in the colonic mucosa was present, and tubular adenomas were widely distributed from the cecum to the rectum with or without low-grade intraepithelial neoplasia (C). After the methylprednisolone-based comprehensive treatment, only mild chronic inflammation was present in the gastric mucosa (B), and scattered tubular adenoma was present in the colon (D)