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Table 5 Bivariable and multivariable logistic regression of PT among liver disease patients attending at the UoG-CSH, Northwest, Ethiopia, 2022 (n = 307)

From: The magnitude and associated factors of coagulation abnormalities among liver disease patients at the University of Gondar Comprehensive Specialized Hospital Northwest, Ethiopia, 2022

Variables

Category

PT

Bivariable analysis

Multivariable

Prolonged PT (%)

Normal PT (%)

COR (95%CI)

P-value

AOR (95%CI)

Sex

Male

146 (66.36)

74 (33.64)

0.75 (0.43, 1.29)

.306

-

Female

63 (72.41)

24 (27.59)

1

 

Age

 < 18 (children)

14(50.00)

14(50.00)

1

 

1

18–45 (young adult)

131 (69.68)

57(30.32)

2.29(1.02, 5.13)

0.042

1.09(0.35, 3.38)

 > 45 (old adult)

64 (70.33)

27(29.67)

2.37(0.99, 5.63)

0.051

0.85(0.25, 2.84)

Residence

Rural

147(69.01)

66(30.99)

1.15(0.68, 1.92)

0.597

-

Urban

62(65.96)

32(34.04)

1

 

Occupation of study participants

Farmer

127(71.75)

50(28.25)

1.56(0.61, 3.99)

0.351

-

Housewife

23(69.70)

10(30.30)

1.41(0.44, 4.47)

0.554

Merchant

11(47.83)

12(52.17)

0.56(0.16, 1.87)

0.351

Private employee

14(73.68)

5(26.32)

1.72(0.44, 6.63)

0.429

Other

21(61.76)

13(38.24)

0.99(0.32, 3.04)

0.992

Government employee

13(61.90)

8(38.10)

1

 

Educational level

No education

101(69.23)

44(30.77)

1.03(0.37, 2.91)

0.943

-

Primary school

76(64.71)

42(35.29)

0.84(0.29, 2.38)

0.752

High school

20(76.92)

6(23.08)

1.53(0.40, 5.81)

0.525

University & college

12(68.42)

6(31.58)

1

 

Marital status

Unmarried

90(71.43)

36(28.57)

1.30(0.79, 2.13)

0.294

-

Married

119(65.75)

62(34.25)

1

 

Use of medication other than liver disease

Yes

58(67.44)

28(32.56)

0.96(0.56, 1.63)

0.881

-

No

151(68.33)

70(31.67)

1

 

History of anemia

Yes

43(84.31)

8(15.69)

2.91(1.31, 6.46)

0.009

2.97(1.26, 7.03)

No

166(64.84)

90(35.16)

1

 

1

Presence of DM

Yes

9(69.23)

4(30.77)

1.05(0.31, 3.52)

0.927

-

No

200(68.03)

94(31.97)

1

 

Presence of cardiac disease

Yes

25(80.65)

6(19.35)

2.08(0.82, 5.25)

0.120

1.87(0.68, 5.15)

No

184(66.67)

92(33.33)

1

 

1

History of blood transfusion

No

192(71.64)

76(28.36)

3.26(1.64, 6.49)

0.003

3.72(1.78, 7.78)

Yes

17(43.59)

22(56.41)

1

 

1

Presence of hypertension

Yes

15(71.43)

6(28.57)

1.18(0.44, 3.15)

0.733

-

No

194(67.83)

92(32.17)

1

 

Tea or coffee drinking habit

No

26(70.27)

11(29.73)

0.97(0.46, 2.04)

0.955

-

Yes

183(67.78)

87(32.22)

1

 

Meat feeding habit

Yes

192(67.61)

92(32.39)

0.73(0.28, 1.93)

0.534

-

No

17(73.91)

6(26.09)

1

 

Vegetable feeding habit

No

58(82.86)

12(17.14)

2.75(1.40, 5.40)

0.003

2.98(1.42, 6.24)

Yes

151(63.71)

86(36.29)

1

 

1

Alcohol drinking habit

Yes

139(67.80)

66(32.20)

0.96(0.57, 1.60)

0.884

-

No

70(68.63)

32(31.37)

1

 

Cigarette smoking habit

Yes

7(63.64)

4(36.36)

0.81(0.23, 2.84)

0.748

-

No

202(68.24)

94(31.76)

1

 

Physical exercise habit

No

187(71.37)

75(28.63)

2.60(1.37, 4.95)

0.003

3.23(1.60, 6.52)

Yes

22(48.89)

23(51.11)

1

 

1

Types of liver disease

CLD

108(68.79)

49(31.21)

2.59(1.25, 5.37)

0.010

3.01(1.10, 8.21)

ALD

20(76.92)

6(23.08)

3.92(1.28, 11.99)

0.017

4.97(1.27, 17.41)

Viral hepatitis

64(73.56)

23(26.44)

3.27(1.46, 7.30)

0.004

3.56(1.19, 10.63)

Acute liver disease

17(45.95)

20(54.05)

1

 

1

Presence of virus hepatitis (HBV and HCV)

Yes

53(60.92)

34(39.08)

0.63(0.38, 1.07)

0.092

0.74(0.42, 1.33)

No

156(70.91)

64(29.09)

1

 

1

  1. Abbreviation: * = Significant Variable, ALD Alcoholic Liver Disease, APTT Activated Partial Thromboplastin Time, CLD Chronic Liver Disease, DMDiabetes millets, AOR, Adjusted odds ratio, CORCrude Odd Ratio, CI Confidence Interval, 1 reference group other includes student and have no jobs