Table 6 Bivariable and multivariable logistic regression of abnormal APTT among liver disease patients attending at the UoG-CSH, Northwest, Ethiopia, 2022 (n = 307)
Variable | Category | APTT | Bivariable analysis | Multivariable analysis | ||
|---|---|---|---|---|---|---|
Abnormal (%) | Normal (%) | P-value | COR (95%CI) | AOR (95%CI) | ||
Sex | Male | 138(62.73) | 82(37.27) | 0.567 | 0.85 (0.50, 1.44) | - |
Female | 57(65.52) | 30(34.48) | 1 | |||
Age | < 18 (children) | 12(42.86) | 16(57.14) | 1 | 1 | |
18–45 (young adult) | 120(63.83) | 68(36.17) | 0.037 | 2.35(1.05, 5.2) | 5.22(1.26, 21.63) | |
> 45 (old adult) | 63(69.23) | 28(30.77) | 0.013 | 3 (1.25, 7.16) | 5.49(1.21, 24.82) | |
Residence | Rural | 136(63.85) | 77(36.15) | 0.856 | 1.03(0.62, 1.72) | - |
Urban | 59(62.77) | 35(37.23) | 1 | |||
Occupation | Farmer | 115(64.97) | 62(35.03) | 0.125 | 2.04(0.82, 5.07) | 1.84(0.66, 5.12) |
Housewife | 22(66.67) | 11(33.33) | 0.168 | 2.20(0.71, 6.75) | 1.59(0.46, 5.50) | |
Merchant | 17(73.91) | 6(26.09) | 0.078 | 3.11(0.87, 11.03) | 3.61(0.94, 13.92) | |
Private employee | 12(63.16) | 7(36.84) | 0.326 | 1.88(0.53, 6.68) | 1.63(0.41, 6.41) | |
Other | 19(55.88) | 15(44.12) | 0.551 | 1.39(0.46, 4.15) | 3.21(0.74, 13.77) | |
Government employee | 10(47.62) | 11(52.38) | 1 | 1 | ||
Educational level | No education | 93(65.03) | 50(34.97) | 0.295 | 1.67(0.63, 4.38) | - |
Primary school | 76(63.87) | 43(36.13) | 0.351 | 1.59(0.59, 4.21) | ||
High school | 16(61.54) | 10(38.46) | 0.551 | 1.44(0.43, 4.77) | ||
University& College | 10(52.63) | 9(47.37) | 1 | |||
Marital status | Unmarried | 80(63.49) | 46(36.51) | 0.994 | 0.99(0.62, 1.60) | - |
Married | 115(63.54) | 66(36.46) | 1 | |||
Use of medication other than liver disease | Yes | 57(66.28) | 29(33.72) | 0.531 | 1.18(0.70,1.99) | |
No | 138(62.44) | 83(37.56) | 1 | |||
History of anemia | Yes | 42(82.35) | 9(17.65) | 0.003 | 3.14(1.46, 6.73) | 3.02(1.34, 6.76) |
No | 153(59.77) | 102(40.23) | 1 | 1 | ||
Presence of DM | Yes | 8(61.54) | 5(38.46) | 0.880 | 0.91(0.29, 2.86) | - |
No | 187(63.61) | 107()36.39 | 1 | |||
Presence of heart disease | Yes | 23(74.19) | 8(25.81) | 0.197 | 1.73(0.75, 4.02) | 1.48(0.61, 3.62) |
No | 172(62.32) | 104(37.68) | 1 | 1 | ||
History of blood transfusion | No | 177(66.04) | 91(33.96) | 0.018 | 2.26(1.15, 4.47) | 2.28(1.09, 4.79) |
Yes | 18(46.15) | 21(53.85) | 1 | 1 | ||
Presence of hypertension | Yes | 12(57.14) | 9(42.86) | 0.531 | 0.75(0.30, 1.84) | - |
No | 183(63.99) | 103(36.01) | 1 | |||
Tea or coffee drinking habit | No | 24(64.86) | 13(35.14) | 0.878 | 1.05(0.15, 2.17) | - |
Yes | 171(63.33) | 99(36.67) | 1 | |||
Meat feeding habit | Yes | 179(63.03) | 105(36.97) | 0.532 | 0.74(0.29, 1.87) | - |
No | 16(69.57) | 7(30.43) | 1 | |||
Vegetable feeding habit | No | 55(78.57) | 15(21.43) | 0.004 | 2.54(1.35, 4.75) | 2.64(1.34, 5.20) |
Yes | 140(59.07) | 97(40.93) | 1 | 1 | ||
Alcohol drinking habit | Yes | 126(61.46) | 79(38.54) | 0.289 | 0.76(0.46, 1.25) | - |
No | 69(67.65) | 33(32.35) | 1 | |||
Cigarette smoking habit | Yes | 6(54.55) | 5(45.45) | 0.531 | 0.67(0.20, 2.27) | - |
No | 189(63.85) | 107(36.15) | 1 | |||
Physical exercise habit | No | 173(66.03) | 89(33.97) | 0.029 | 2.03(1.07, 3.84) | 2.35(1.16, 4.78) |
Yes | 22(48.89) | 23(51.11) | 1 | 1 | ||
Type of liver disease | CLD | 92(58.60) | 65(41.40) | 0.838 | 1.07(0.52, 2.22) | 0.53(0.18, 1.53) |
ALD | 19(73.08) | 7(26.92) | 0.189 | 2.06(0.69, 6.11) | 1.17(0.28, 4.81) | |
Viral hepatitis | 63(72.41) | 24(27.59) | 0.090 | 2(0.89, 4.46) | 0.94(0.30, 2.95) | |
Acute liver disease | 21(56.76) | 16(43.24) | 1 | 1 | ||
Presence of virus hepatitis (HBV and HCV) | Yes | 50(57.47) | 37(42.53) | 0.167 | 0.69(0.42, 1.16) | 0.88(0.50, 1.55) |
No | 145(65.91) | 75(34.09) | 1 | 1 | ||