Skip to main content

Table 1 Characteristics of genetic variants proxied for intercellular adhesion molecule 4

From: Intercellular adhesion molecule 4 and ischemic stroke: a two-sample Mendelian randomization study

SNP

Chr

Position (build 37)

Nearest Gene

EA

OA

EAF

Beta

SE

P value

rs113415585

1

25,554,998

SYF2

A

G

0.03694

-0.5040

0.0739

9.12 × 10− 12

rs149152056*

1

25,705,424

RHCE

T

C

0.03092

-0.4119

0.0711

6.92 × 10− 9

rs2375113

1

25,525,915

SYF2

G

A

0.20298

0.2540

0.0301

3.31 × 10− 17

rs28608145

1

25,520,341

SYF2

G

C

0.97613

-0.6041

0.0875

5.01 × 10− 12

rs4649080*

1

25,737,116

RHCE

T

C

0.08227

-0.4015

0.0484

1.02 × 10− 16

rs61774838

1

25,482,196

IFITM3P7

A

G

0.13531

-0.2645

0.0381

4.07 × 10− 12

rs72660908

1

25,583,610

RSRP1

G

C

0.45371

-0.6177

0.0230

4.68 × 10− 159

rs72660919

1

25,677,605

TMEM50A

A

G

0.16694

0.3113

0.0376

1.35 × 10− 16

rs760970

1

25,578,944

RSRP1

G

A

0.88987

-0.5808

0.0389

1.86 × 10− 50

rs79017607

1

25,519,831

SYF2

C

T

0.03393

0.4519

0.0713

2.34 × 10− 10

rs79561453

1

25,564,304

SYF2

C

G

0.05498

-0.4092

0.0577

1.29 × 10− 12

  1. *Proxy SNPs (rs150766331 and rs116137570) correlated (r2 > 0.8) with SNPs that were not available in the MEGASTROKE dataset
  2. Abbreviations: SNP: single-nucleotide polymorphism; Chr: chromosome; EA: effect allele; OA: other allele; EAF, effect allele frequency; SE: standard error