Table 2 Outcomes in the intermediate-dose and standard-dose prophylactic anticoagulation groups
Total N = 1174 | Intermediate N = 775 | Standard N = 399 | Crude difference (95%CI) | p value | |
|---|---|---|---|---|---|
Vital status on day 90 | |||||
Dead, n (%) | 211 (18) | 125 (16) | 86 (21) | -5.4 (-10.2 to -0.6) | - |
Alive, out of the ICU, n (%) | 945 (80) | 634 (82) | 311 (78) | 4.0 (-0.9 to 8.9) | |
Alive, still in the ICU, n (%) | 17 (1) | 15 (2) | 2 (0.5) | 1.4 (0.2 to 2.6) | |
Secondary endpoints | |||||
ICU stay length, days, mean (SD) | 16 (18) | 16 (19) | 15.84 (17) | 1.1 (-1.2 to 3.3) | - |
DVT, n (%) | 107 (9) | 59 (7) | 48 (12) | -4.4 (-8.1 to -0.7) | 0.013 |
PE, n (%) | 108 (9) | 55 (7) | 53 (13) | -6.2 (-10.0 to -2.4) | 0.0005 |