Table 1 Baseline characteristica of patients included comparing pulmonary embolism (PE) and non-PE group. A p-value < 0.05 was considered significant. Values are given as n (%) or median [IQR]. DVT (deep vein thrombosis), CRP (C-reactive protein), BMI (body mass index), IQR (inter quartile range).

All

N = 310

N = 48

Age

65.1 [53.4;76.8]

73.2 [56.7;80.1]

0.054

Sex:

male

200 (64.5%)

32 (66.7%)

0.898

female

110 (35.5%)

16 (33.3%)

Smoker:

0.433

former

27 (8.71%)

5 (10.4%)

no

251 (81.0%)

35 (72.9%)

unknown

18 (5.81%)

4 (8.33%)

yes

14 (4.52%)

4 (8.33%)

BMI

34.8 [29.1;40.0]

40.7 [27.1;42.6]

0.500

Reason for hospitalisation

0.270

COVID-19

279 (90.0%)

40 (83.3%)

other reason

24 (7.74%)

6 (12.5%)

unknown

7 (2.26%)

2 (4.17%)

Previous dvt or PE

11 (3.55%)

3 (6.25%)

0.414

Ongoing dvt

0 (0.00%)

1 (2.08%)

0.134

Arterial hypertension

161 (51.9%)

26 (54.2%)

0.894

Hematologic malignancy

11 (3.55%)

0 (0.00%)

0.372

Solid tumor

0.193

metastatic

10 (3.23%)

0 (0.00%)

no

278 (89.7%)

42 (87.5%)

unknown

17 (5.48%)

6 (12.5%)

yes

5 (1.61%)

0 (0.00%)

Symptoms/signs of dvt

13 (4.19%)

6 (12.5%)

0.029

Dyspnea

152 (49.0%)

25 (52.1%)

0.812

Chestpain

43 (13.9%)

6 (12.5%)

0.975

Abnormal fatigue

102 (32.9%)

14 (29.2%)

0.727

Fever

132 (42.6%)

16 (33.3%)

0.292

Cough

124 (40.0%)

20 (41.7%)

0.951

Dizziness

22 (7.10%)

4 (8.33%)

0.764

Hemoptysis

7 (2.26%)

1 (2.08%)

1,000

Oxygen saturation

95.0 [92.0;96.0]

94.0 [92.5;96.0]

0.301

Blood pressure systolic

136 [121;150]

140 [126;156]

0.410

Blood pressure diastolic

79.0 [70.0;86.0]

80.0 [74.0;90.5]

0.189

Pulse frequency

90.0 [77.0;98.0]

90.5 [82.0;99.0]

0.686

Glasgow Coma Scale

15.0 [15.0;15.0]

15.0 [15.0;15.0]

0.669

Laboratory measurements

D-Dimer maximum value (µg/ml)

1.40 [1.00;2.70]

3.90 [1.60;11.4]

< 0.001

CRP maximum value (mg/dl)

6.85 [3.42;12.4]

10.2 [5.50;14.6]

0.016

Interleukin 6 maximum value (pg/ml)

60.4 [31.2;125]

93.7 [46.1;189]

0.013

Hematocrit maximum value (l/l)

0.38 [0.34;0.42]

0.39 [0.36;0.43]

0.269

Hemoglobin maximum value (g/dl)

13.1 [11.8;14.6]

13.4 [12.3;15.0]

0.213

Glucose maximum value (mg/dl)

124 [108;152]

127 [105;148]

0.996

Creatinine maximum value (Jaffé; mg/dl)

1.00 [0.80;1.30]

1.00 [0.80;1.30]

0.615

Gamma-glutamyltransferase maximum value (U/l)

48.5 [29.0;91.0]

57.0 [36.8;140]

0.320

Alanine transferase (ALT/GOT) maximum value (U/l)

46.0 [33.0;66.0]

49.0 [36.8;72.2]

0.289

Aspartate aminotransferase (AST/GPT) maximum value (U/l)

36.0 [23.0;56.0]

44.0 [29.0;65.0]

0.138

Creatine kinase maximum value (U/l)

116 [58.5;295]

118 [52.5;315]

0.994

Admission worst COVID Stage (Leoss)

0.147

Complicated

100 (32.3%)

22 (45.8%)

Critical

23 (7.42%)

5 (10.4%)

Uncomplicated

178 (57.4%)

21 (43.8%)

Unknown

9 (2.90%)

0 (0.00%)

Outcome worst COVID stage (Leoss)

0.362

Complicated

128 (41.3%)

21 (43.8%)

Critical

72 (23.2%)

13 (27.1%)

Death

36 (11.6%)

8 (16.7%)

Uncomplicated

67 (21.6%)

5 (10.4%)

Unknown

7 (2.26%)

1 (2.08%)

Outcome discharge

0.087

Death

37 (11.9%)

8 (16.7%)

Discharge home

209 (67.4%)

24 (50.0%)

Discharge to care facility

50 (16.1%)

13 (27.1%)

Discharge to other hospital

9 (2.90%)

1 (2.08%)

Unknown

5 (1.61%)

2 (4.17%)