Table 1 General characteristics of study populations

Sex

 Male, n (%)

51 (57.3)

38 (57.6)

45 (51.1)

15 (53.6)

Age

 Median in years (IQR)

54.7 (43.4 – 60.8)

54.8 (46.0 – 60.7)

51.0 (42.0 – 59.0)

51.0 (42.3 – 58.5)

Body Mass Index (BMI)

 < 20 kg m⁻², n (%)

1 (1.1)

0 (0.0)

3 (3.4)

1 (3.6)

 20—25 kg m⁻², n (%)

28 (31.8)

19 (29.2)

25 (28.7)

8 (28.6)

 25—30 kg m⁻², n (%)

39 (44.3)

30 (46.2)

36 (41.4)

11 (39.3)

 > 30 kg m⁻², n (%)

20 (22.7)

16 (24.6)

23 (26.4)

8 (28.6)

At least one comorbidity

 Yes, n (%)

16 (18.2)

12 (18.5)

8 (9.2)

1 (3.6)

Infection last 2 months

 Yes, n (%)

8 (9.4)

7 (11.1)

11 (12.6)

6 (21.4)

Smoking

 Yes: currently, n (%)

20 (23.0)

18 (28.1)

18 (20.7)

7 (25.0)

 Yes: formerly, n (%)

30 (34.5)

25 (39.1)

35 (40.2)

11 (39.3)

Current use oral contraceptives^a

 Yes, n (%) of women

3 (8.3)

1 (3.7)

4 (9.8)

3 (23.1)

Malignancy last year

 Yes, n (%)

1 (1.1)

1 (1.5)

1 (1.1)

0 (0.0)

ABO-blood type

 Homozygote non-O, n (%)

6 (7.2)

5 (8.2)

12 (14.0)

1 (3.7)

 Heterozygote O, n (%)

42 (50.6)

31 (50.8)

41 (47.7)

14 (51.9)

 Homozygote O, n (%)

35 (42.2)

25 (41.0)

33 (38.4)

12 (44.4)

Factor V Leiden

 Yes: heterozygote, n (%)

3 (3.6)

2 (3.3)

6 (7.0)

2 (7.4)

 No, n (%)

80 (96.4)

59 (96.7)

80 (93.0)

25 (92.6)

Type of lower-leg injury

 Ankle distortion, n (%)

1 (1.1)

1 (1.5)

NA

NA

 Contusion, n (%)

1 (1.1)

0 (0.0)

 Achilles’ tendon rupture, n (%)

5 (5.7)

2 (3.0)

 Foot fracture, n (%)

53 (59.6)

42 (63.6)

 Ankle fracture, n (%)^b

29 (32.6)

21 (31.8)

Surgical treatment of injury

 Yes, n (%)

12 (13.5)

9 (13.6)

NA

NA

Time between trauma and blood draw

 Within 24 h, n (%)

62 (70.5)

45 (69.2)

NA

NA

 Within 7 days, n (%)

21 (23.9)

17 (26.2)

 After 7 days, n (%)

5 (5.7)

3 (4.6)

Administration of prophylactic LMWH (after blood draw)

 Yes, n (%)

42 (47.2)

31 (47.0)

48 (54.5)

14 (50.0)