Table 2 Correlation between initial/follow-up D-dimer levels and stroke severity, mechanism, and complications during the acute phase: simple linear regression analysis

Initial NIHSS score [IQR]

0.036 (0.020 to 0.052)

< 0.001

0.032 (0.015 to 0.049)

< 0.001

Early neurological deterioration, (%)

0.470 (0.197 to 0.743)

0.001

0.604 (0.321 to 0.888)

< 0.001

Stroke mechanism, (%)

Large artery atherosclerosis

-0.214 (-0.473 to 0.044)

0.104

-0.308 (-0.578 to -0.038)

0.026

Small-vessel occlusion

-0.408 (-0.729 to -0.087)

0.013

-0.274 (-0.613 to 0.065)

0.113

Cardioembolism

0.291 (0.025 to 0.558)

0.032

0.131 (-0.151 to 0.413)

0.361

Other determined

1.344 (0.767 to 1.921)

< 0.001

1.434 (0.830 to 2.039)

< 0.001

Undetermined

0.019 (-0.281 to 0.318)

0.903

0.154 (-0.160 to 0.467)

0.335

Cancer, n (%)

0.584 (0.252 to 0.915)

0.001

0.575 (0.226 to 0.924)

0.001

Active cancer, n (%)

0.830 (0.418 to 1.242)

< 0.001

1.017 (0.590 to 1.443)

< 0.001

Venous thromboembolism, n (%)^†

0.759 (0.177 to 1.341)

0.011

1.128 (0.606 to 1.650)

< 0.001

Use of anticoagulants, n (%)

0.291 (-0.006 to 0.588)

0.055

0.014 (-0.300 to 0.328)

0.931