Clinical significance of D-dimer levels during acute period in ischemic stroke

Thrombosis Journal

Table 4 Multivariable logistic regression analysis to evaluate the effects of initial and follow-up D-dimer levels on early neurological deterioration

	Crude OR (95% CI)	P-value	Adjusted OR (95% CI)	P-value
Initial D-dimer
Age	1.01 [0.98–1.04]	0.578	1.01 [0.98–1.04]	0.457
Male sex	0.65 [0.36–1.17]	0.150	0.78 [0.40–1.51]	0.459
Initial NIHSS score	1.06 [1.02–1.10]	0.002	1.03 [0.98–1.08]	0.203
Fasting glucose^*	5.91 [1.97–17.78]	0.002	3.99 [1.15–13.89]	0.030
WBC counts^*	2.96 [1.33–6.58]	0.008	2.20 [0.83–5.82]	0.114
Initial D-dimer^*	1.61 [1.20–2.16]	0.001	1.48 [1.06–2.05]	0.020
Follow-up D-dimer
Age	1.01 [0.98–1.04]	0.578	1.01 [0.98–1.04]	0.504
Male sex	0.65 [0.36–1.17]	0.150	0.79 [0.40–1.53]	0.483
Initial NIHSS score	1.06 [1.02–1.10]	0.002	1.03 [0.98–1.08]	0.226
Fasting glucose^*	5.91 [1.97–17.78]	0.002	3.86 [1.09–13.64]	0.036
WBC counts^*	2.96 [1.33–6.58]	0.008	2.13 [0.81–5.61]	0.127
Follow-up D-dimer^*	1.79 [1.33–2.41]	< 0.001	1.60 [1.16–2.20]	0.004

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