Table 3 Association between early thromboprophylaxis and mortality by admission diagnosis

Overall

Thromboprophylaxis status

 Yes

Ref

 No

1.35 (1.31–1.40)

< 0.001

 Contraindicated

1.35 (1.31–1.40)

< 0.001

 Not indicated

1.22 (0.94–1.12)

0.522

Admission diagnosis

Head trauma (with or without multi trauma) (n = 15,618)

 Yes

Ref

 No

1.23 (0.97–1.56)

0.090

 Contraindicated

1.20 (0.95–1.51)

0.115

 Not indicated

1.71 (1.08–2.69)

0.020

Cardiac arrest (n = 29,498)

 VTE prophylaxis

 Yes

Ref

 No

1.85 (1.65–2.07)

< 0.001

 Contraindicated

1.37 (1.16–1.62)

< 0.001

 Not indicated

1.29 (1.91–2.75)

< 0.001

Intracerebral haemorrhage (n = 7,448)

 Yes

Ref

 No

1.48 (1.19–1.84)

< 0.001

 Contraindicated

1.14 (0.96–1.37)

0.136

 Not indicated

2.41 (1.52–3.82)

< 0.001

Subarachnoid haemorrhage (n = 6,598)

 Yes

Ref

 No

1.09 (0.79–1.50)

0.582

 Contraindicated

0.97 (0.74–1.26)

0.824

 Not indicated

1.38 (0.73–2.59)

0.316

Stroke (n = 11,615)

 Yes

Ref

 No

1.26 (1.05–1.52)

0.014

 Contraindicated

1.07 (0.90–1.27)

0.457

 Not indicated

1.16 (0.82–1.63)

0.392