Fig. 2
From: Circulating LPS from gut microbiota leverages stenosis-induced deep vein thrombosis in mice
Treatment of mice with prebiotics or probiotics suppresses DVT. (A) The alteration of fecal microbiome was analyzed between control (CON) and XOS-treated mice. The bar graph shows the LDA scores, with green bars indicating genus enriched in the XOS group and red bars indicating genus enriched in the CON group. (B-D) The partial IVC ligation procedure was performed after feeding mice with xylooligosaccharides (XOS, n = 8) for 4 weeks. After 24 h, the IVC tissues were harvested, and the formed thrombi were quantified and imaged, and the results were compared to those formed in CON mice (n = 11). (E-G) The partial IVC ligation procedure was performed on mice treated with a probiotic cocktail including Bifidobacterium, Lactobacillus and Enterococcus (BLE, n = 11), or saline buffer as CON (n = 13) for 4 weeks. After 24 h, the formed thrombi in the IVC tissues of these mice were quantified and imaged. Data are presented as mean ± SD. (*, p < 0.05; **, p < 0.01)