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Table 3 Cox proportional hazard regression analysis for incident cardiovascular disease based on the atherogenic index of plasma trajectory groups

From: Longitudinal trajectories of atherogenic index of plasma and risks of cardiovascular diseases: results from the Korean genome and epidemiology study

 

AIP trajectory groups

 

Decreasing

Increasing

Number, n

3036

2807

 

Incident CVD case, n

115

163

 

Follow-up period, person-year

22055.2

20101.3

 

Incidence rate per 1000 person-year

5.21

8.11

 
 

HR

HR (95% CI)

P value

Incident CVD risk

   

Unadjusted

1 (reference)

1.57 (1.47–2.00)

< 0.001

Model 1

1 (reference)

1.43 (1.12–1.83)

0.004

Model 2

1 (reference)

1.34 (1.04–1.73)

0.022

Model 3

1 (reference)

1.31 (1.02–1.69)

0.037

  1. Model 1: adjusted for age, sex, and body mass index
  2. Model 2: adjusted for variables included in model 1 plus smoking status, drinking status, physical activity, and total energy intake
  3. Model 3: adjusted for variables included in model 2 plus hypertension, diabetes mellitus, and serum C-reactive protein
  4. Abbreviations: AIP, atherogenic index of plasma, CVD, cardiovascular disease; CI, confidence interval; HR, hazard ratio