Fig. 6From: GDF15 affects venous thrombosis by promoting EndMT through smad2/p-smad2 pathwayThe possible mechanism of GDF15 in VTE. GDF15 plays an important role in the cytokine-induced EndMT process of endothelial cells. Inhibition of GDF15 expression can inhibit the EndMT process, further inhibit the coagulation and improve the fibrinolysis function of endothelial cells, and thus reduce the local fiber deposition of thrombosisBack to article page