The serum lipid profiles in immune thrombocytopenia: Mendelian randomization analysis and a retrospective study

Thrombosis Journal

Table 3 Pleiotropy analysis

outcome	exposure	MR-Egger		MR-PRESSO
outcome	exposure	egger_intercept	P-value	Raw P-value	Outlier-corrected P-value	Global Test P-value
PDW	ApoA1	-0.0023889	0.07525349	< 0.001	< 0.001	< 0.001
PDW	ApoB	0.00182644	0.29193778	0.040	0.005	< 0.002
PDW	HDL-C	0.00078889	0.55968876	< 0.001	< 0.001	< 0.003
PDW	triglycerides	-0.0017449	0.08720377	< 0.001	< 0.001	< 0.004
MPV	LDL-C	-0.0001743	0.88624577	0.067	0.002	< 0.005

PDW: Platelet distribution width, MPV: Mean platelet volume, ApoA1: apolipoprotein A-1, ApoB: apolipoprotein B, HDL-C: high-density-lipoprotein cholesterol, LDL-C: low-density-lipoprotein cholesterol

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