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Table 4 Baseline clinical and laboratory characteristics of participants

From: The serum lipid profiles in immune thrombocytopenia: Mendelian randomization analysis and a retrospective study

 

Total (N)

male (N)

Female (N)

P

Age(years) t

47.10 ± 18.13(457)

47.60 ± 19.97(196)

46.70 ± 16.63(261)

0.594

Platelet indices t

    

PC (×109/L)

29.5 ± 44.48(449)

29.0 ± 42.90(193)

29.9 ± 45.72(256)

0.822

PDW (fL)

15.65 ± 3.24(167)

15.31 ± 3.29(77)

15.94 ± 3.19(90)

0.213

MPV (fL)

11.93 ± 1.84(167)

11.69 ± 1.72(77)

12.13 ± 1.93(90)

0.124

PCT (%)

0.06 ± 0.06(167)

0.06 ± 0.06(77)

0.07 ± 0.07(90)

0.574

Lipid profile t

    

Cho (mmol/L)

4.58 ± 1.19(407)

4.35 ± 1.27(170)

4.75 ± 1.10(237)

0.001**

HDL-C (mmol/L)

1.16 ± 0.36(406)

1.04 ± 0.31(169)

1.25 ± 0.37(237)

< 0.001**

LDL-C (mmol/L)

2.76 ± 0.93(406)

2.68 ± 1.04(169)

2.82 ± 0.83(237)

0.128

sdLDL (mmol/L)

0.83 ± 0.47(398)

0.87 ± 0.47(165)

0.80 ± 0.46(233)

0.171

ApoA1(mmol/L)

1.33 ± 0.29(106)

1.26 ± 0.29(45)

1.38 ± 0.29(61)

0.031*

ApoB (mmol/L)

1.01 ± 0.30(111)

0.95 ± 0.27(47)

1.04 ± 0.32(64)

0.128

TG (mmol/L)

1.69 ± 2.49(408)

1.69 ± 1.18(171)

1.68 ± 3.11(237)

0.975

LPA (mmol/L)

39.0 ± 53.86(105)

29.72 ± 31.07(45)

46.11 ± 65.39(60)

0.092

Hcy (mmol/L)

14.54 ± 7.64(403)

17.90 ± 8.63(169)

12.12 ± 5.74(234)

< 0.001**

NEFA (mmol/L)

51.30 ± 34.12(405)

46.30 ± 22.77(169)

54.90 ± 39.99(236)

0.012*

PLA2(mmol/L)

569.0 ± 120.25(49)

565.0 ± 137.43(25)

573.0 ± 102.16(24)

0.826

  1. Data were shown as mean ± standard deviation (number of cases) or positive percentage (number of positive cases / total cases).
  2. PC: platelet count, PDW: platelet distribution width, MPV: mean platelet volume, PCT: plateletcrit, Cho: cholesterol, HDL-C: high-density-lipoprotein cholesterol, LDL-C: low-density-lipoprotein cholesterol, sdLDL: small dense low-density-lipoprotein, ApoA1: apolipoprotein A-1, ApoB: apolipoprotein B, TG: triglyceride, LPA: lipoprotein A, Hcy: homocysteine, NEFA: non-esterified fatty acid, PLA2: phospholipase A2.
  3. t student’s t test, χχ2 test.
  4. *P < 0.05, ** P < 0.01; P < 0.05 as significant difference, shown in bold font.