From: Venous thromboembolic disease in admitted blunt trauma patients: what matters?
Variable | VTE (n = 177) | No VTE (n = 10,749) | P |
---|---|---|---|
Age (years, median, IQR) | 62 [48–79] | 67 [45–82] | 0.32 |
Male Sex | 67.8% | 53.0% | 0.0001 |
Two or more comorbidities | 50.3% | 52.4% | 0.63 |
Anticoagulant | 10.2% | 11.5% | 0.65 |
Antiplatelet | 10.7% | 7.6% | 0.16 |
Anticoagulant + Antiplatelet | 18.6% | 18.2% | 0.97 |
Disseminated cancer and/or receiving chemotherapy | 3.4% | 1.1% | 0.002 |
Motor vehicle crash + motorcycle crash | 13.6%+22.6% | 17.5%+5.5% | 0.0005 |
Fall | 49.7% | 61.8% | 0.003 |
Other | 14.9% | 15.1% | 0.96 |
Body Mass Index$ (median, IQR) | 28.4 [24.6–32.0] | 26.2 [23.3–29.8] | < 0.0001 |
Injury Severity Score | 16 [9-27] | 9 [5-14] | < 0.0001 |
Abdomen Abbreviated Injury Score (AIS) ≥ 3 | 12.4% | 4.5% | < 0.0001 |
Head/neck AIS ≥ 3 | 39.0% | 22.3% | < 0.0001 |
Face AIS ≥ 3 | 1.1% | 0.2% | 0.07 |
Chest AIS ≥ 3 | 29.9% | 17.0% | < 0.0001 |
Extremity AIS ≥ 3 | 50.3% | 25.7% | < 0.0001 |
External AIS ≥ 3 | 0.6% | 0.1% | 0.18 |
Surgery in Operating Room (%)$$ | 87.6% | 45.2% | < 0.0001 |
Inferior Vena Cava filter (%) | 35.0% | 0.15% | < 0.0001 |
Central line/Peripherally inserted central catheter (%) | 32.8% | 5.1% | < 0.0001 |
Mechanical Ventilation (%) | 47.4% | 9.9% | < 0.0001 |
Intensive Care Unit stay (%) | 68.9% | 27.0% | < 0.0001 |
Hosp LOS (days, median, IQR) | 21 [14–36] | 6 [4-10] | < 0.0001 |
Intensive Care Unit LOS (days, median, IQR) | 14 [7-22] | 0 [0–2] | < 0.0001 |
Non-VTE complications (%) | 45.2% | 8.2% | < 0.0001 |
Mortality (%) | 6.8% | 2.8% | 0.004 |
Chemoprophylaxis (%)* | |||
None | 41.8% | 24.7% | < 0.0001 |
subcutaneous heparin | 42.9% | 54.9% | 0.002 |
prophylactic enoxaparin | 13.5% | 18.4% | 0.12 |
coumadin | 0.56% | 0.8% | 0.52 |
miscellaneous | 1.1% | 0.6% | 1 |
VTE Location (%) | |||
Infrageniculate only | 13.0% | n/a | n/a |
Suprageniculate only | 22.6% | n/a | n/a |
Infrageniculate + suprageniculate | 24.9% | n/a | n/a |
Lower extremity NFS | 0.56% | n/a | n/a |
Upper extremity | 5.6% | n/a | n/a |
Upper extremity + infrageniculate + suprageniculate | 0.56% | n/a | n/a |
PE only | 24.9% | n/a | n/a |
PE + infrageniculate | 2.2% | n/a | n/a |
PE + suprageniculate | 1.1% | n/a | n/a |
PE + infrageniculate + suprageniculate | 3.9% | n/a | n/a |
PE + upper extremity | 0.56% | n/a | n/a |
Days from admission to index VTE (median, IQR) | 6 [3-11] | n/a | n/a |
≤1 day from admission to index VTE | 7.3% | n/a | n/a |