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Table 3 Distribution of the detected genotypes according to gender

From: Molecular patterns of alpha-thalassemia in the kingdom of Saudi Arabia: identification of prevalent genotypes and regions with high incidence

Genotypes

Gender

 

Total

P value

P value

 

Female

Male

   

No Mutation Detected

N

%

41

59.4%

28

40.6%

69

100.0%

0.31

 

--SEA/ αα

N

%

3

37.5%

5

62.5%

8

100.0%

0.48

 

- α3.7/ αTSaudiα

N

%

15

36.6%

26

63.4%

41

100.0%

0.03*

 

- α3.7IVS1(−5nt)α

N

%

8

72.7%

3

27.3%

11

100.0%

0.24

 

αIVS1 (−5nt)α/ αTSaudiα

N

%

5

38.5%

8

61.5%

13

100.0%

0.40

 

- α3.7/ - α4.2α

N

%

1

100.0%

0

0.0%

1

100.0%

1.0

 

--MED/αTTurkishα

N

%

1

100.0%

0

0.0%

1

100.0%

1.0

 

- α3.7/- α3.7

N

%

74

45.4%

89

54.6%

163

100.0%

0.02*

0.04*

- α3.7/ αα

N

%

77

62.1%

47

37.9%

124

100.0%

0.04*

 

αTSaudiα/αTSaudiα

N

%

7

50.0%

7

50.0%

14

100.0%

0.79

 

αTSaudiα / αα

N

%

20

64.5%

11

35.5%

31

100.0%

0.27

 

αIVS1 (−5nt)α / αIVS1 (−5nt)α

N

%

3

42.9%

4

57.1%

7

100.0%

0.71

 

αIVS1 (−5nt)α/ αα

N

%

74

57.4%

55

42.6%

129

100.0%

0.32

 

--MED/αα

N

%

5

38.5%

8

61.5%

13

100.0%

0.40

 

Total

N

%

334

53.4%

291

46.6%

625

100.0%

0.09

 
  1. * P < 0.05