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Table 4 Genotype frequencies and their distribution according to the Saudi cities

From: Molecular patterns of alpha-thalassemia in the kingdom of Saudi Arabia: identification of prevalent genotypes and regions with high incidence

Cities

 

Genotype

  

Total

(%)

P value

P value

  

Deletional Mutation

Deletional &non-deletional mutation

Non-deletional Mutation

   

Makkah

N

%

66

51.6%

10

7.8%

52

40.6%

128

100.0%

0.04*

0.004**

Riyadh

N

%

38

74.5%

2

3.9%

11

21.6%

51

100.0%

0.02*

 

Jeddah

N

%

61

43.8%

10

7.3%

68

48.9%

139

100.0%

0.001**

 

Medina

N

%

2

28.6%

2

28.6%

3

42.9%

7

100.0%

0.15

 

Taif

N

%

41

55.4%

7

9.5%

26

35.1%

74

100.0%

0.9

 

Jizan

N

%

14

51.9%

5

18.5%

8

29.6%

27

100.0%

0.26

 

Jubail

N

%

11

57.9%

3

15.8%

5

26.3%

19

100.0%

0.54

 

Al-Ahassa

N

%

47

68.1%

13

18.8%

9

13.0%

69

100.0%

0.001**

 

Al-Baha

N

%

6

100.0%

0

0.0%

0

0.0%

6

100.0%

0.09

 

Khamis Mushait

N

%

4

57.1%

0

0.0%

3

42.9%

7

100.0%

0.67

 

Khobar

N

%

2

100.0%

0

0.0%

0

0.0%

2

100.0%

0.45

 

Dammam

N

%

5

55.6%

0

0.0%

4

44.4%

9

100.0%

0.57

 

Tabuk

N

%

2

50.0%

1

25.0%

1

25.0%

4

100.0%

0.56

 

Abha

N

%

4

80.0%

0

0.0%

1

20.0%

5

100.0%

0.51

 

Abu Arish

N

%

4

57.1%

0

0.0%

3

42.9%

7

100.0%

0.67

 

Hail

N

%

1

100.0%

0

0.0%

0

0.0%

1

100.0%

NA*

 

Najran

N

%

1

100.0%

0

0.0%

0

0.0%

1

100.0%

NA*

 

Total

N

%

309

55.6%

53

9.5%

194

34.9%

556

100.0%

  
  1. * P < 0.05, ** P < 0.01
  2. NA: Not applicable