Table 1 Demographic and clinical characteristics of patients with failed and successful thromboprophylaxis
From: Factors associated with venous thromboembolic disease due to failed thromboprophylaxis
Variable | Failed thromboprophylaxis n = 204 | Effective thromboprophylaxis n = 408 | p value | |
|---|---|---|---|---|
Male, n (%) | 107 (52.45) | 214 (52.45) | 1 | |
Age in years, median (IQR) | 63 (51–74) | 63 (51–74) | 1 | |
Type of thromboprophylaxis, n (%) | ||||
Dalteparin Enoxaparin Sodium heparin | 2 (1.0) 188 (92.1) 14 (6.9) | 4 (1.0) 376 (92.1) 28 (6.9) | 1 | |
BMI, kg/m2 median (IQR) | 26.3 (23.6–30.1) | 25.2 (22.2–29.0) | < 0.001 | |
Permanent central venous catheter, n (%) | 9 (4.4) | 18 (4.4) | 1 | |
Active cancer, n (%) | 59 (28.9) | 121 (29.7) | 0.851 | |
History of VTE, n (%) | 7 (3.4) | 12 (2.9) | 0.742 | |
Indication for hospitalization, n (%) | ||||
Medic Non-orthopedic surgical Orthopedic Surgical Neurosurgery Obstetrician | 168 (82.3) 24 (11.8) 8 (3.9) 4 (2.0) 0 (0) | 312 (76.5) 58 (14.2) 29 (7.1) 6 (1.5) 3 (0.7) | 0.268 | |
Surgery, n (%)* | 38 (18.6) | 91 (22.3) | 0.293 | |
Missed dose, n (%) | ||||
0 1–2 3–4 > 5 | 140 (68.6) 46 (22.6) 8 (3.9) 10 (4.9) | 297 (72.8) 74 (18.1) 27 (6.6) 10 (2.5) | 0.116 | |
Leukocytosis, n (%) | 55 (27.0) | 77 (18.9) | 0.022 | |
Transfusion of blood products, n (%) | ||||
Packaged red blood cells Platelets Fresh frozen plasma Various | 30 (14.7) 1 (0.5) 1 (0.5) 7 (3.4) | 48 (11.8) 6 (1.5) 2 (0.5) 13 (3.2) | 0.704 | |
ICU requirement, n (%) | 98 (48.0) | 101 (24.8) | < 0.001 | |
Infection with SARS COV 2, n (%) | 96 (47.1) | 135 (33.1) | < 0.001 | |
Type of embolic event, n (%) | ||||
PTE DVT PE y DVT | 109 (53.4) 74 (36.3) 21 (10.3) | - - - | - - - | |