|  | AT deficiency n = 77 | PC deficiency n = 48 | PS deficiency n = 313 | Total n = 438 | Control n = 1,178,337 |
---|---|---|---|---|---|---|
Body weight of term newborn babies (mean ± SD, g) | 2784 ± 413.0 | 2827 ± 546.1 | 2852 ± 499.0 | 2837 ± 290.1 | 2861 ± 566.3 | |
Sex | Male | 38 | 25 | 168 | 231Â (52.5%) | 606,354 (51.3%) |
Female | 37 | 23 | 149 | 209 (47.5%) | 574,518 (48.7%) | |
Apgar score | 1 min (mean ± SD) | 8.1 ± 1.2 | 7.9 ± 1.3 | 8.0 ± 1.3 | 8.0 ± 1.3 | 8.0 ± 1.4 |
5 min (mean ± SD) | 9.1 ± 0.6 | 9.1 ± 0.7 | 9.0 ± 0.9 | 9.0 ± 0.8 | 8.9 ± 1.1 | |
Full term delivery (37 ≤  < 42 GW) | Large for gestational age (LGA) | 0 | 1 | 2 | 3 (0.8%) | 8818 (0.9%) |
Appropriate for gestational age (AGA) | 57 | 36 | 245 | 338 (86.4%) | 909,762 (89.7%) | |
Small for gestational age (SGA) | 12* | 6 | 32 | 50* (12.8%) | 95,434 (9.4%) | |
Preterm delivery (22 ≤  < 37 GW) | 10 | 5 | 43 | 58 (13.2%) | 162,229 (13.8%) | |
Multiple pregnancy | 2 | 0 | 9‡ | 11# (2.5%) | 74,310 (6.3%) | |
Non reassuring fetal status | 0‡ | 4 | 8# | 12§ (2.7%) | 90,742 (7.7%) | |
Neonatal asphyxia (5 min Apgar score < 7) | 2* | 1* | 6§ | 9§ (2.1%) | 125,653 (10.7%) | |
Deformity | 2 | 1 | 7 | 10 (2.3%) | 15,990 (1.4%) | |
Neonatal death | 0 | 0 | 2 | 2 (0.5%) | 7115 (0.6%) | |
Other complications | 3 | 5 | 12 | 20 (4.6%) | nd | |
Mean enzyme activity of newborn (mean ± SD, %) | 51.5 ± 43.1 | 13.0 ± 0.00 | 58.6 ± 32.1 | 36.2 ± 23.9 | nd |