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Table 1 Patient Characteristics According to Prokaryote-Specific DNA in Thrombi

From: Detecting prokaryote-specific gene and other bacterial signatures in thrombi from patients with acute ischemic stroke

 

Prokaryote-Specific DNA

p value

+

n = 26

−

n = 55

 

Age, media (IQR)

72 (65–75)

69 (57–78)

0.46

Male gender, n (%)

20 (76.9)

32 (58.2)

0.10

BMI, media (IQR)

23.9 (21.5–25.4)

24.1 (23.2–26.1)

0.55

Hypertension

16 (61.5)

37 (67.3)

0.61

Diabetes

8 (30.8)

11 (20.0)

0.29

AF

16 (61.5)

33 (60.0)

0.62

CAD

9 (34.6)

12 (21.8)

0.22

Prior stroke

7 (26.9)

11 (20.0)

0.48

Smoking

11 (42.3)

13 (23.6)

0.09

Alcohol drinking

10 (38.5)

9 (16.4)

0.03*

Intravenous alteplase use

3 (11.5)

9 (16.4)

0.74

NIHSS score, media (IQR)

16 (11–22)

18 (14–25)

0.08

Stroke sub-type, n (%)

  

0.19

 LAA

7 (26.9)

13 (23.6)

 

 Cardioembolic

16 (61.5)

29 (52.8)

 

 Others or uncertain

3 (11.6)

13 (23.6)

 

HDL, mmol/L, media (IQR)

1.18 (0.84–1.40)

1.11 (0.87–1.38)

0.79

LDL, mmol/L, media (IQR)

2.68 (1.44–3.06)

2.49 (2.01–2.98)

0.98

TG, mmol/L, media (IQR)

0.68 (0.53–1.06)

0.96 (0.67–1.26)

0.08

TC, mmol/L, media (IQR)

3.89 (3.21–4.87)

4.26 (3.43–4.55)

0.98

Leukocyte, ×109/L, media (IQR)

10.01 (8.06–13.06)

9.39 (7.88–12.60)

0.27

CRP, mg/L, media (IQR)

3.55 (0.50-13.09)

9.9 (3.60–23.50)

0.17

Occlusion site, n (%)

  

0.75

 ICA

9 (34.6)

19 (34.5)

 

 MCA

15 (57.7)

28 (50.9)

 

 Vertebrobasilar

2 (7.7)

8 (14.5)

 

Procedure time, media (IQR)

66 (55–95)

85 (58–120)

0.14

Thrombus fragmentation, n (%)

9 (34.6)

30 (54.5)

0.09

Successful reperfusion, n (%)

24 (92.3)

42 (76.4)

0.13

  1. BMI, body mass index; AF, Atrial fibrillation; CAD, coronary atherosclerosis disease; NIHSS, National Institute of health stroke scale; LAA, large-artery atherosclerosis; CRP, C-reactive protein; HDL, high density lipoprotein cholesterol; LDL, low density lipoprotein cholesterol; TG, Triglycerides; TC, Total cholesterol; ICA, internal carotid artery; MCA, middle cerebral artery