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Table 3 Long term risk of death due to CV and cancer in DVT and PE patients in the study. Multivariable model adjusted by comorbidities (diabetes, hypertension, heart failure, chronic obstructive pulmonary disease, chronic kidney disease, stroke, atrial fibrillation, and cancer) and medications at baseline (anticoagulants, antihypertensive, lipid lowering). CI = confidence interval, CV = cardiovascular, DVT = deep vein thrombosis, PE = pulmonary embolism, HR = hazard ratio

From: Causes of death after first time venous thromboembolism

All-cause mortality

Control

DVT

PE

Crude HR (95% CI)

Ref

2.5(2.3–2.6)

5.5 (5.1–5.8)

Age- and sex-adjusted HR (95% CI)

Ref

1.6(1.5–1.8)

3.0(2.9–3.3)

*Multivariable adjusted HR (95% CI)

 

1.7 (1.5–1.8)

3.4 (3.1–3.6)

CV death

   

Crude HR (95% CI)

Ref

1.5 (1.2–1.8)

3.5 (3.0-4.1)

Age- and sex-adjusted HR (95% CI)

Ref

0.9 (0.8–1.1)

2.0(1.7–2.2)

*Multivariable adjusted HR (95% CI)

 

1.0 (0.9–1.3)

2.2(1.9–2.6)

All cancer death

   

Crude HR (95% CI)

Ref

4.6 (4.2–5.1)

10.4 (9.5–11.4)

Age- and sex-adjusted HR (95% CI)

Ref

3.1 (2.8–3.4)

6.0 (5.5–6.6)

*Multivariable adjusted HR (95% CI)

 

2.7 (2.4–3.1)

5.4 (4.9-6.0)