Association of inherited thrombophilia mutations and their combinations among palestinian women with unexplained recurrent miscarriage

Table 1 Prevalence of hereditary thrombophilia mutations among unexplained RM patients and controls

Mutation	Patients	Controls	P value	Patients	Controls	P value	Patients	Controls	P value
Mutation	Mutant %		P value	Hetero %		P value	Homo Mutant %		P value
FVL R506Q	20	18	0.719	19	18	0.856	1	0	0.317
FII G20210A	1	3	0.314	1	3	0.314	0	0	1.0
MTHFR C677T	51	53	0.778	43	36	0.313	8	17	0.055
MTHFR A1298C	64	47	0.016	48	37	0.117	16	10	0.208
BFG − 455G > A	45	35	0.150	36	26	0.127	9	9	1.0
PAI1 5G/4G	63	69	0.372	48	50	0.778	15	19	0.453
FXIIIA V34L	27	16	0.059	21	15	0.271	6	1	0.055
FV HR2 H1299R	15	18	0.569	13	17	0.429	2	1	0.562

Data are expressed as Mutant %: Mutant includes both heterozygotes and mutant homozygotes; Hetero %: Heterozygous %; Homo mutant %: Homozygous mutant. Data was analysis by the N-1 chi-squared test and a p value < 0.05 was considered significant. The p-value in bold font was used to stress the significant values or values less than 0.05.

ISSN: 1477-9560