Table 2 Characteristics of training and validation sets

Age

67.89 ± 6.35

68.50 ± 6.32

0.292

BMI

26.16 ± 3.55

25.68 ± 3.10

0.369

Gender

0.368

 Male

122 (35.1%)

45 (30.4%)

 Female

226 (64.9%)

103 (69.6%)

High blood pressure

0.503

 Yes

175 (50.3%)

80 (54.1%)

 No

173 (49.7%)

68 (45.9%)

Diabetes mellitus

0.702

 Yes

46 (13.2%)

17 (11.5%)

 No

302 (86.8%)

131 (88.5%)

Coronary heart disease

0.797

 Yes

22 (6.3%)

11 (7.4%)

Characteristics

Training set

Validation set

p value

 No

326 (93.7%)

137 (92.6%)

White blood cell

1

 Abnormal

15 (4.3%)

6 (4.1%)

 Normal

333 (95.7%)

142 (95.9%)

Red blood cell

0.653

 Abnormal

118 (33.9%)

54 (36.5%)

 Normal

230 (66.1%)

94 (63.5%)

Hemoglobin

1

 Abnormal

0 (0%)

0 (0%)

 Normal

348 (100%)

148 (100%)

Hematocrit

0.671

 Abnormal

130 (37.4%)

59 (39.9%)

 Normal

218 (62.6%)

89 (60.1%)

Mean Corpuscular Volume

0.115

 Abnormal

11 (3.2%)

10 (6.8%)

 Normal

337 (96.8%)

138 (93.2%)

Mean corpuscular hemoglobin

0.548

 Abnormal

13 (3.7%)

8 (5.4%)

 Normal

335 (96.3%)

140 (94.6%)

Mean corpuscular hemoglobin concentration

0.451

 Abnormal

35 (10.1%)

11 (7.4%)

 Normal

313 (89.9%)

137 (92.6%)

Red blood cell volume distribution width SD

0.303

 Abnormal

72 (20.7%)

24 (16.2%)

 Normal

276 (79.3%)

124 (83.8%)

Red blood cell volume distribution width CV

0.828

 Abnormal

59 (17%)

27 (18.2%)

 Normal

289 (83%)

121(81.8%)

Platelet

0.723

 Abnormal

19 (5.5%)

10 (6.8%)

 Normal

329 (94.5%)

138 (93.2%)

Platelet crit

0.552

 Abnormal

61 (17.5%)

30 (20.3%)

 Normal

287 (82.5%)

118 (79.7%)

Mean Platelet Volume

0.963

 Abnormal

87 (25%)

36 (24.3%)

 Normal

261 (75%)

112 (75.7%)

Platelet-larger cell ratio

0.963

 Abnormal

87 (25%)

36 (24.3%)

 Normal

261 (75%)

112 (75.7%)

Platelet distribution width

0.262

 Abnormal

172 (49.4%)

82 (55.4%)

 Normal

176 (50.6%)

66 (44.6%)

Characteristics

Training set

Validation set

p value

Neutrophil

0.325

 Abnormal

18 (5.2%)

4 (2.7%)

 Normal

330 (94.8%)

144 (97.3%)

Lymphocyte

0.394

 Abnormal

34 (9.8%)

19 (12.8%)

 Normal

314 (90.2%)

129 (87.2%)

Monocyte

0.074

 Abnormal

35 (10.1%)

24 (16.2%)

 Normal

313 (89.9%)

124 (83.8%)

Eosinophils

1

 Abnormal

329 (94.5%)

140 (94.6%)

 Normal

19 (5.5%)

8 (5.4%)

Basophil

0.410

 ≥ 0.06

41 (11.8%)

13 (8.8%)

 <0.06

307 (88.2%)

135 (91.2%)

Neutrophil%

0.641

 Abnormal

16 (4.6%)

9 (6.1%)

 Normal

332 (95.4%)

139 (93.9%)

Lymphocyte%

0.202

 Abnormal

32 (9.2%)

20 (13.5%)

 Normal

316 (90.8%)

128 (86.5%)

Monocyte%

0.330

 Abnormal

316 (90.8%)

139 (93.9%)

 Normal

32 (9.2%)

9 (6.1%)

Eosinophils%

1

 Abnormal

23 (6.6%)

10 (6.8%)

 Normal

325 (93.4%)

138 (93.2%)

Basophil%

0.285

 ≥ 1

33 (9.5%)

9 (6.1%)

 <1

315 (90.5%)

139 (93.9%)

Alanine amino transferase

0.953

 Abnormal

26 (7.5%)

12 (8.1%)

 Normal

322 (92.5%)

136 (91.9%)

Aspartate amino transferase

0.828

 Abnormal

32 (9.2%)

12 (8.1%)

 Normal

316 (90.8%)

136 (91.9%)

AST/ALT

0.247

 Abnormal

4 (1.1%)

4 (2.7%)

 Normal

344 (98.9%)

144 (97.3%)

Total bilirubin

1

 >21

14 (4%)

6 (4.1%)

 ≤ 21

334 (96%)

142 (95.9%)

Direct bilirubin

1

Characteristics

Training set

Validation set

p value

 >4

13 (3.7%)

6 (4.1%)

 ≤ 4

335 (96.3%)

142 (95.9%)

Indirect bilirubin

1

 Abnormal

330 (94.8%)

140 (94.6%)

 Normal

18 (5.2%)

8 (5.4%)

Total protein

0.368

 Abnormal

288 (82.8%)

128 (86.5%)

 Normal

60 (17.2%)

20 (13.5%)

Serum albumin

0.409

 Abnormal

152 (43.7%)

58 (39.2%)

 Normal

196 (56.3%)

90 (60.8%)

Globulin

1

 Abnormal

0 (0%)

0 (0%)

 Normal

348 (100%)

148 (100%)

A/G

0.517

 Abnormal

79 (22.7%)

29 (19.6%)

 Normal

269 (77.3%)

119 (80.4%)

Blood Urea Nitrogen

0.502

 Abnormal

62 (17.8%)

22 (14.9%)

 Normal

286 (82.2%)

126 (85.1%)

Creatinine

0.955

 Abnormal

73 (21%)

30 (20.3%)

 Normal

275 (79%)

118 (79.7%)

K

0.201

 Abnormal

34 (9.8%)

21 (14.2%)

 Normal

314 (90.2%)

127 (85.8%)

Na

0.193

 Abnormal

20 (5.7%)

14 (9.5%)

 Normal

328 (94.3%)

134 (90.5%)

CL

1

 Abnormal

29 (8.3%)

13 (8.8%)

 Normal

319 (91.7%)

135 (91.2%)

Ca

1

 Abnormal

27 (7.8%)

12 (8.1%)

 Normal

321 (92.2%)

136 (91.9%)

Procalcitonin

0.639

 ≥ 0.51

27 (7.8%)

9 (6.1%)

 <0.51

321 (92.2%)

139 (93.9%)

Glucose

 Abnormal

0 (0%)

0 (0%)

 Normal

348 (100%)

148 (100%)

PT

0.194

 Abnormal

44 (12.6%)

26 (17.6%)

Characteristics

Training set

Validation set

p value

 Normal

304 (87.4%)

122 (82.4%)

INR

0.323

 Abnormal

4 (1.1%)

0 (0%)

 Normal

344 (98.9%)

148 (100%)

PT%

0.267

 Abnormal

16 (4.6%)

3 (2%)

 Normal

332 (95.4%)

145 (98%)

FIB

0.714

 Abnormal

30 (8.6%)

15 (10.1%)

 Normal

318 (91.4%)

133 (89.9%)

APTT

0.250

 Abnormal

13 (3.7%)

2 (1.4%)

 Normal

335 (96.3%)

146 (98.6%)

TT

0.740

 Abnormal

7 (2%)

4 (2.7%)

 Normal

341 (98%)

144 (97.3%)

D-Dimer

0.658

 ≥ 0.55

95 (27.3%)

44 (29.7%)

 <0.55

253 (72.7%)

104 (70.3%)

C reactive protein

0.863

 <5

48 (13.8%)

22 (14.9%)

 ≥ 5

300 (86.2%)

126 (85.1%)