Table 1 Characteristics of the patients on Rivaroxaban 20 or Rivaroxaban 15

Age (years)

73

(59–87)

71

(59–80)

76

(63–87)

< 0.001

Gender, female/male

28/32

9/21

19/11

p = 0.02

Weight (kg)

84

(60–140)

90

(60–140)

79

(60–134)

p = 0.004

Hypertension

54

(90%)

26

(87%)

28

(93%)

p = 0.671

Diabetes

13

(22%)

4

(13%)

9

(30%)

p = 0.210

Chronic heart failure

14

(23%)

6

(20%)

8

(27%)

p = 0.760

Peripheral Artery Obstructive Disease

2

(3%)

1

(3%)

1

(3%)

p = 1.000

Ischemic Heart Disease

12

(20%)

6

(20%)

6

(20%)

p = 0.747

Cerebrovascular Insult

8

(13%)

3

(10%)

5

(17%)

p = 0.480

CHA₂DS₂VASc score:

2.1 +/-1.3

1.8 +/- 1.3

2.5 +/- 1.2

p = 0.048

HAS-BLED Score

1.1+/-0.6

0.9 +/-0.7

1.2 +/-0.5

p = 0.028

Bleeding events (yes/no)

28

13

15

p = 0.796

Bleeding severity (major/minor)

3/25

2/11

1/14

p = 0.664

Thromboembolic events

3

2

1

p = 1.000