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Table 2 The characteristics of new tests and diagnostics

From: C-type lectin-like receptor 2: roles and drug target

Model/Index

Disease/Application

Humanized CLEC-2 mouse model

Screened out small-molecule inhibitors [77]

Drug screening system

Screened out small-molecule inhibitors [78]

sCLEC-2/ pCLEC-2↑

Coronary artery disease [79]

Acute ischemic stroke [80–81]

COVID-19 [82]

C2PAC↑

Coagulation function in patients with sepsis [83]

Postoperative VTE formation [85]

  1. sCLEC-2, soluble CLEC-2; pCLEC-2, plasma CLEC-2; C2PAC, sCLEC-2/platelet count ratio; COVID-19, coronavirus Disease 2019; VTE, venous thromboembolism