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  1. Lupus anticoagulant-hypoprothrombinemia syndrome (LAHPS) is characterized by bleeding and thrombosis in patients with autoimmune diseases or infections. Paediatric LAHPS exhibits various degrees of bleeding, r...

    Authors: Atsushi Sakamoto, Masao Ogura, Atsushi Hattori, Kinji Tada, Reiko Horikawa, Hisaya Nakadate, Kimikazu Matsumoto, Keiji Nogami, Masahiro Ieko and Akira Ishiguro
    Citation: Thrombosis Journal 2021 19:19
  2. Determination of anticoagulant therapy is of pronounced interest in emergency situations. However, routine tests do not provide sufficient insight. This study was performed to investigate the impact of anticoa...

    Authors: Philipp Groene, Daniela Wagner, Tobias Kammerer, Lars Kellert, Andreas Giebl, Steffen Massberg and Simon Thomas Schäfer
    Citation: Thrombosis Journal 2021 19:18
  3. We conducted a prospective observational study for investigating the changes in the 13th member of a disintegrin-like and metalloprotease with thrombospondin type 1 motif (ADAMTS13) and its association with th...

    Authors: Hironori Matsumoto, Jun Takeba, Kensuke Umakoshi, Satoshi Kikuchi, Muneaki Ohshita, Suguru Annen, Naoki Moriyama, Yuki Nakabayashi, Norio Sato and Mayuki Aibiki
    Citation: Thrombosis Journal 2021 19:17
  4. Polycythemia vera (PV) is characterized by red cell mass expansion in the peripheral blood and can be complicated with thrombosis, bleeding, evolution to acute myeloid leukemia (AML) or a fibrotic phase. Parox...

    Authors: Sevastianos Chatzidavid, Nefeli Giannakopoulou, Panagiotis Theodorou Diamantopoulos, Eleni Gavriilaki, Panagiota Katsiampoura, Eleftheria Lakiotaki, Stratigoula Sakellariou, Nora-Athina Viniou and Georgios Dryllis
    Citation: Thrombosis Journal 2021 19:16
  5. COVID-19 appears to be associated with a high risk of venous thromboembolism (VTE). We aimed to systematically review and meta-analyze the risk of clinically relevant VTE in patients hospitalized for COVID-19.

    Authors: Gregoire Longchamp, Sara Manzocchi-Besson, Alban Longchamp, Marc Righini, Helia Robert-Ebadi and Marc Blondon
    Citation: Thrombosis Journal 2021 19:15
  6. Arterial and venous thrombosis are reported to be common in critically ill COVID-19 patients.

    Authors: Chuen Wen Tan, Bingwen Eugene Fan, Winnie Z. Y. Teo, Moon Ley Tung, Humaira Shafi, Dheepa Christopher, Shuwei Zheng, Wee Ming Peh, Stephrene Seok Wei Chan, Vanessa Cui Lian Chong, Christian Aledia Gallardo, Cheng Chieh Ray Chang, Li Min Ling, Jing Yuan Tan, Ken Cheah Hooi Lee, Ghee Chee Phua…
    Citation: Thrombosis Journal 2021 19:14
  7. Several observational studies have reported the rate of venous and arterial thrombotic events in patients infected with COVID-19, with conflicting results. The aim of this study was to estimate the rate of thr...

    Authors: Abdulrahman Al Raizah, Ahmed Al Askar, Naila Shaheen, Khalid Aldosari, Mohamed Alnahdi, Musumadi Luhanga, Turki Alshuaibi, Wail Bajhmoum, Khaled Alharbi, Ghaida Alsahari, Hadeel Algahtani, Eunice Alrayes, Abdulrahim Basendwah, Alia Abotaleb and Mosaad Almegren
    Citation: Thrombosis Journal 2021 19:13
  8. In patients with infectious diseases, disseminated intravascular coagulation (DIC) is often diagnosed without the fibrinogen value. The relationship between hypofibrinogenemia and outcomes of DIC in infectious...

    Authors: Kazuo Kawasugi, Hideo Wada, Goichi Honda, Noriaki Kawano, Toshimasa Uchiyama, Seiji Madoiwa, Naoki Takezako, Kei Suzuki, Yoshinobu Seki, Takayuki Ikezoe, Toshiaki Iba and Kohji Okamoto
    Citation: Thrombosis Journal 2021 19:12
  9. Mechanical removal of a thrombus by thrombectomy can be quite challenging. For reasons that are not fully understood, some thrombi require multiple passes to achieve successful recanalization, whereas other th...

    Authors: Senna Staessens, Olivier François, Linda Desender, Peter Vanacker, Tom Dewaele, Raf Sciot, Karen Vanhoorelbeke, Tommy Andersson and Simon F. De Meyer
    Citation: Thrombosis Journal 2021 19:11
  10. Severe thromboembolic events are one of the major complications associated with COVID-19 infection, especially among critically ill patients. We analysed ROTEM measurements in COVID-19 patients with a severe d...

    Authors: Kristina Boss, Andreas Kribben and Bartosz Tyczynski
    Citation: Thrombosis Journal 2021 19:10
  11. There is a growing body of evidence showing substantial underuse of appropriate venous thromboembolism (VTE) prophylaxis in patients at risk. In the present study, our goal was to assess the current practices ...

    Authors: Imad Hajj, Mahmoud AL-Masri, Kaldoun Bashaireh, Mohammed Bani Hani, Shadi Hamouri, Joe Khouzami, Nisrine Sabra and Chahine Fadel
    Citation: Thrombosis Journal 2021 19:9
  12. The progression of coagulation in COVID-19 patients with confirmed discharge status and the combination of autopsy with complete hemostasis parameters have not been well studied.

    Authors: Tiebin Jiang, Bo Lv, Hongxia Liu, Shiwen He, Guogang Zhang, Chanyi Li, Wanqiong Li, Weilin Li, Yaqi He, Tong Zhang, Yunyun Wang, Wu Mo, Ning Yi, Luying Peng, Ying Li, Chunhong Ruan…
    Citation: Thrombosis Journal 2021 19:8
  13. Left ventricular thrombus (LVT) is not uncommon and pose a risk of systemic embolism, which can be mitigated by adequate anticoagulation. Direct oral anticoagulants (DOACs) are increasingly being used as alter...

    Authors: Tarun Dalia, Shubham Lahan, Sagar Ranka, Amandeep Goyal, Sara Zoubek, Kamal Gupta and Zubair Shah
    Citation: Thrombosis Journal 2021 19:7
  14. The optimal anticoagulant scheme during catheter-directed thrombolysis (CDT) for deep venous thrombosis (DVT) remains unknown. This study was performed to evaluate the feasibility of anticoagulation therapy us...

    Authors: Yonghui Li, Junwei Wang, Rongzhou He, Junmeng Zheng, Zhibo Chen, Chen Yao and Kai Huang
    Citation: Thrombosis Journal 2021 19:6
  15. The coronavirus infection 2019 (COVID-19) is associated with microvascular endothelial injury. Here, we report that syndecan-1, a component of endothelial glycocalyx, may reflect the disease state of COVID-19 ...

    Authors: Keiko Suzuki, Hideshi Okada, Hiroyuki Tomita, Kazuyuki Sumi, Yoshinori Kakino, Ryu Yasuda, Yuichiro Kitagawa, Tetsuya Fukuta, Takahito Miyake, Shozo Yoshida, Akio Suzuki and Shinji Ogura
    Citation: Thrombosis Journal 2021 19:5
  16. Heparin-induced thrombocytopenia with thrombosis (HITT) is a paradoxical prothrombotic complication of anticoagulant therapy. As many as 3% of patients undergoing cardiac surgery develop clinical HIT presentin...

    Authors: Joseph Ferry, Samuel Youssef, Pierce Wu and Livia Hegerova
    Citation: Thrombosis Journal 2021 19:4
  17. Post-thrombotic syndrome (PTS) is a frequent chronic complication of proximal deep vein thrombosis (DVT) of the lower limb, but predictors of PTS are not well established. We aimed to examine predictors of PTS...

    Authors: Marit Engeseth, Tone Enden, Per Morten Sandset and Hilde Skuterud Wik
    Citation: Thrombosis Journal 2021 19:3
  18. A considerable number of SARS-CoV-2 infected individuals could be asymptomatic and don’t need medical treatment. The clinical spectrum of SARS-CoV-2 infection ranges from asymptomatic cases, medium-intensity f...

    Authors: Franca Del Nonno, Daniele Colombo, Roberta Nardacci and Laura Falasca
    Citation: Thrombosis Journal 2021 19:1
  19. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Kochawan Boonyawat, Pichika Chantrathammachart, Pawin Numthavaj, Nithita Nanthatanti, Sithakom Phusanti, Angsana Phuphuakrat, Pimjai Niparuck and Pantep Angchaisuksiri
    Citation: Thrombosis Journal 2020 18:39

    The original article was published in Thrombosis Journal 2020 18:34

  20. Extracorporeal membrane oxygenation (ECMO) support can be life-saving in critically ill COVID-19 patients. However, there are many complications associated with this procedure, including Heparin-induced thromb...

    Authors: Xuan T. Phan, Tuan H. Nguyen, Tung T. Tran, Thu-Hien T. Huynh, Thuy-Ha T. Hoang, Vinh-Chau V. Nguyen and Thao N. T. Pham
    Citation: Thrombosis Journal 2020 18:37
  21. Thromboembolism is one of the main causes of maternal mortality, which can be prevented in many cases. The present study was designed to investigate the incidence and prophylaxis strategies for maternal mortal...

    Authors: Mahboobeh Shirazi, Behrokh Sahebdel, Mahnoosh Torkzaban, Elham Feizabad and Marjan Ghaemi
    Citation: Thrombosis Journal 2020 18:36
  22. Alcohol consumption is associated with haemostasis and so may influence cardiovascular conditions. It is unknown whether the association of alcohol with total and γ’ fibrinogen concentrations, as well as clot ...

    Authors: Petro Hannie Rautenbach, Cornelie Nienaber-Rousseau and Marlien Pieters
    Citation: Thrombosis Journal 2020 18:35
  23. Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, the incidence of thromboembolism has been increasingly reported. The aim of this systematic review was to explore the incidence of venou...

    Authors: Kochawan Boonyawat, Pichika Chantrathammachart, Pawin Numthavaj, Nithita Nanthatanti, Sithakom Phusanti, Angsana Phuphuakrat, Pimjai Niparuck and Pantep Angchaisuksiri
    Citation: Thrombosis Journal 2020 18:34

    The Correction to this article has been published in Thrombosis Journal 2020 18:39

  24. There is a high incidence of deep vein thrombosis (DVT) among cancer patients undergoing chemotherapy. Chemotherapy-induced vascular endothelial cell activation (VECA) is characterized by increased plasma leve...

    Authors: Budi Setiawan, Cecilia Oktaria Permatadewi, Baringin de Samakto, Ashar Bugis, Ridho M. Naibaho, Eko Adhi Pangarsa, Damai Santosa and Catharina Suharti
    Citation: Thrombosis Journal 2020 18:33
  25. Pregnant women are at increased risk of thrombotic adverse events. Plasma derived immune globulin (IG) products, which are used in pregnancy for various indications, may contain procoagulant impurity activated...

    Authors: Yanqun Xu, Yideng Liang, Leonid Parunov, Daryl Despres, Michael Eckhaus, Dorothy Scott, Mikhail Ovanesov and Evi B. Struble
    Citation: Thrombosis Journal 2020 18:32
  26. In the intensive care unit (ICU), patients with thrombocytopenia are at high risk for bleeding and should be assessed for their thrombogenic potential. However, the analytical conditions of conventional hemost...

    Authors: Bengo Atari, Takashi Ito, Tomoka Nagasato, Tomoko Ohnishi, Kazuya Hosokawa, Tomotsugu Yasuda, Ikuro Maruyama and Yasuyuki Kakihana
    Citation: Thrombosis Journal 2020 18:31
  27. Hypertensive disorders of pregnancy are associated with vascular complications, including ischemic stroke and cervical artery dissection. Vertebral artery dissection (VAD), however, is rare. We describe a 31-y...

    Authors: Nicholas T. Manasewitsch, Ahmed A. Hanfy, Bryce D. Beutler, Daniel Antwi-Amoabeng, Moutaz Taha, Mohamed Elnaggar and Gurpreet S. Chahal
    Citation: Thrombosis Journal 2020 18:30
  28. Left ventricular thrombus (LVT) is associated with a significant risk of ischemic stroke (IS) and peripheral embolization. Societal guidelines recommend the use of warfarin, with direct oral anticoagulants (DO...

    Authors: Zafar Ali, Nicholas Isom, Tarun Dalia, Farhad Sami, Uzair Mahmood, Zubair Shah and Kamal Gupta
    Citation: Thrombosis Journal 2020 18:29
  29. Direct endothelial injury by viruses and dysregulation of clotting mechanisms due to cytokine storm are the major precipitating factors of mortality in COVID-19; both are attributed to a fundamental dysregulat...

    Authors: Nobunao Ikewaki, Kosagi-Sharaf Rao, Armando Durant Archibold, Masaru Iwasaki, Rajappa Senthilkumar, Senthilkumar Preethy, Shojiro Katoh and Samuel J. K. Abraham
    Citation: Thrombosis Journal 2020 18:27
  30. This study aimed to investigate the predictive value of the D-dimer level for venous thromboembolism (VTE) events during puerperium of women age at 35 years or older, as well as to identify other risk factors ...

    Authors: Wen Hu, Dong Xu, Juan Li, Cheng Chen, Yuan Chen, Fangfang Xi, Feifei Zhou, Xiaohan Guo, Baihui Zhao and Qiong Luo
    Citation: Thrombosis Journal 2020 18:26
  31. Disseminated intravascular coagulation (DIC) can be correctly redefined as disseminated intravascular microthrombosis based on “two-path unifying theory” of in vivo hemostasis. “DIC” is a form of vascular micr...

    Authors: Jae C. Chang
    Citation: Thrombosis Journal 2020 18:25
  32. Air travel thrombosis continues to be a controversial topic. Exposure to hypoxia and hypobaric conditions during air travel is assumed a risk factor. The aim of this study is to explore changes in parameters o...

    Authors: Anna Levkovsky, Rima Dardik, Daniel Barazany, David M. Steinberg, Mark Dan Kirichenko, Sara Apter, Edna Peleg, Daniel Silverberg, Ehud Grossman and Ophira Salomon
    Citation: Thrombosis Journal 2020 18:24
  33. The role of venous obstructions as a risk factor for recurrent venous thromboembolism has never been evaluated. This study aimed to determine whether there is a difference in prevalence of venous obstructions ...

    Authors: Pascale Notten, Rob H. W. Strijkers, Irwin Toonder, Hugo ten Cate and Arina J. ten Cate-Hoek
    Citation: Thrombosis Journal 2020 18:23
  34. Hospitals in the Middle East Gulf region have experienced an influx of COVID-19 patients to their medical wards and intensive care units. The hypercoagulability of these patients has been widely reported on a ...

    Authors: Bassam Atallah, Wasim El Nekidy, Saad I. Mallah, Antoine Cherfan, Laila AbdelWareth, Jihad Mallat and Fadi Hamed
    Citation: Thrombosis Journal 2020 18:22
  35. Coronavirus disease 2019 (COVID-19) is associated with extreme inflammatory response, disordered hemostasis and high thrombotic risk. A high incidence of thromboembolic events has been reported despite thrombo...

    Authors: M. Hardy, T. Lecompte, J. Douxfils, S. Lessire, J. M. Dogné, B. Chatelain, S. Testa, I. Gouin-Thibault, Y. Gruel, R. L. Medcalf, H. ten Cate, G. Lippi and F. Mullier
    Citation: Thrombosis Journal 2020 18:17
  36. Hemostatic changes and endothelial activations have been recognized in β-thalassemic patients after matched-donor hematopoietic stem cell transplantation (HSCT) but there are limited studies for haploidentical...

    Authors: Surapong Lertthammakiat, Peerasit Sitthirat, Usanarat Anurathapan, Duantida Songdej, Samart Pakakasama, Ampaiwan Chuansumrit, Nattaphat Putawornsub, Sawitt Sirasittikarn, Sataporn Wantanawijarn, Praguywan Kadegasem, Suradej Hongeng and Nongnuch Sirachainan
    Citation: Thrombosis Journal 2020 18:21
  37. Patients infected with SARS-CoV-2 often develop venous and arterial thrombosis. The high patient mortality is partly attributed to thrombotic events. An emerging trend is the presence of immunological phenomen...

    Authors: Michael Tran, Chirag Sheth, Rohan Bhandari, Scott J. Cameron and Deborah Hornacek
    Citation: Thrombosis Journal 2020 18:16
  38. Whether glutathione S-transferase (GST) null polymorphisms, namely GSTM1 null, GSTP1 null and GSTT1 null polymorphisms, influence the risk of coronary artery disease (CAD) or not remains unclear. Thus, the author...

    Authors: Hongling Su, Yunshan Cao, Jing Li, Yan Zhu and Xuming Ma
    Citation: Thrombosis Journal 2020 18:20
  39. Upon vascular damage, the exposed subendothelial matrix recruits circulating platelets to site of injury while inducing their firm adhesion mainly via GPVI-collagen interaction. GPVI also supports aggregatory ...

    Authors: Ehteramolsadat Hosseini, Saba Hojjati, Safoora Afzalniaye gashti and Mehran Ghasemzadeh
    Citation: Thrombosis Journal 2020 18:18
  40. Rivaroxaban has the most available data to support the use of prothrombin complex concentrates (PCC) as a reversal agent. However, PCC might increase the incidence of thrombotic events by shifting the haemosta...

    Authors: Lorine Giffard-Quillon, Helene Desmurs-Clavel, Claire Grange, Yohann Jourdy and Yesim Dargaud
    Citation: Thrombosis Journal 2020 18:15
  41. Anticoagulants are commonly prescribed in medical practices and could be of significant harm in the case of medication errors. We conducted a retrospective observational study to determine the frequency and co...

    Authors: Ramin Rahmanzade, Francisco Cabrera Diaz, Claudia Zaugg, Philipp Schuetz and Ali Reza Salili
    Citation: Thrombosis Journal 2020 18:14
  42. Left atrial septal pouches (LASPs) are a relatively newly described but common anatomical cardiac variant thought to be associated with atrial fibrillation (AF) and cardio-embolic stroke. Blue toe syndrome (BT...

    Authors: Snehasis Pradhan, Kciku Gresa, Jan-Peter Röing genannt Nölke and Hans-Joachim Trappe
    Citation: Thrombosis Journal 2020 18:13
  43. Bechet’s disease (BD) is a relatively rare disease that causes recurrent oral and genital ulcers in addition to a variety of systemic manifestations. Concomitant superior-vena-cava (SVC) thrombosis and cardiac...

    Authors: Ahmed M. Elzanaty, Mohammed T. Awad, Ashu Acharaya, Ebrahim Sabbagh, Eman Elsheikh and Moshrik AbdAlamir
    Citation: Thrombosis Journal 2020 18:12
  44. Although numerous replication case-control studies have attempted to determine the association between Factor V Leiden (FVL) 1691G > A mutation and susceptibility to Recurrent pregnancy loss (RPL), there have ...

    Authors: Mohammad Masoud Eslami, Majid khalili, Mina Soufizomorrod, Saeid Abroun and Bahman Razi
    Citation: Thrombosis Journal 2020 18:11
  45. Dual therapy with a direct oral anticoagulant (DOAC) plus a P2Y12 receptor inhibitor is recommended in patients with nonvalvular atrial fibrillation who undergo percutaneous coronary intervention. Thus, we evalua...

    Authors: Ippei Ikushima, Takaaki Akasaka, Yoshiyuki Morishima, Atsushi Takita, Tomoko Motohashi and Tetsuya Kimura
    Citation: Thrombosis Journal 2020 18:10
  46. Advanced pancreatic ductal adenocarcinoma (aPDAC) patients have a lifetime all type thromboembolic event (ATTE) rate of 25–35%. Efficacy and safety of increased dose primary thromboprophylaxis (IDPTP) with low...

    Authors: Anthony Maraveyas, Farzana Haque, Iqtedar Ahmed Muazzam, Waqas Ilyas and George Bozas
    Citation: Thrombosis Journal 2020 18:9

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  • Thrombosis Journal is the official journal of the Asian-Pacific Society on Thrombosis and Hemostasis.

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