Table 1 Presenting characteristics of APL patients who developed thrombotic events
From: Risk factors of thrombosis in Chinese subjects with acute promyelocytic leukemia
Characteristics of Patients | Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | Patient 6 | Patient 7 |
|---|---|---|---|---|---|---|---|
Age(years)/sex | 27/M | 27/F | 22/M | 45/M | 53/F | 55/M | 67/F |
WBC(×109/L) | 3.7 | 2.5 | 3.7 | 106.8 | 14.5 | 0.6 | 3.9 |
HGB(g/L) | 56 | 59 | 99 | 46 | 57 | 67 | 71 |
PLT(×109/L) | 9 | 36 | 2 | 7 | 24 | 62 | 19 |
Risk stratification | Intermediate | Intermediate | Intermediate | High | High | Low | Intermediate |
PML/RARα isoforms | Bcr1 | Bcr3 | Bcr1 | Bcr3 | Bcr3 | Bcr3 | Bcr3 |
Leukemic cell biomarks | CD2- | CD2- | CD2- | CD2- | CD2- | CD2- | CD2- |
CD15- | CD15+ | CD15+ | CD15+ | CD15+ | CD15+ | CD15+ | |
WT1 mutation status | negative | positive | negative | negative | positive | positive | positive |
FLT3/ITD mutation status | negative | positive | positive | positive | positive | positive | positive |
PAI-1 gene polymorphism | 4G4G | 4G5G | 4G5G | 4G4G | 4G4G | 4G4G | 4G4G |