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  1. Gender-related differences in incidence of arterial thrombosis have been a focus of interest for years. The platelet integrin αIIbβ3 is primarily responsible for the interaction between platelets and fibrinoge...

    Authors: Robert Loncar, Reiner B Zotz, Christoph Sucker, Aleksandar Vodovnik, Mario Mihalj and Rüdiger E Scharf
    Citation: Thrombosis Journal 2007 5:5
    Content type: Original basic research Published on:

  3. Monitoring of antiplatelet therapy in patients at cardiovascular risk is difficult because existing platelet function tests are too sophisticated for clinical routine. The whole blood TEG® Platelet Mapping™ assay...

    Authors: Louise Bochsen, Bo Wiinberg, Mads Kjelgaard-Hansen, Daniel A Steinbrüchel and Pär I Johansson
    Citation: Thrombosis Journal 2007 5:3
    Content type: Original clinical investigation Published on:

  4. Platelet adhesion and subsequent thrombus formation on a subendothelial matrix at the site of vascular damage play a crucial role in the arrest of posttraumatic bleeding but also in different pathological thro...

    Authors: Robert Loncar, Volker Stoldt, Sabine Hellmig, Rainer B Zotz, Mario Mihalj and Rüdiger E Scharf
    Citation: Thrombosis Journal 2007 5:2
    Content type: Original basic research Published on:

  5. Recommendations for urgent reversal of oral anticoagulation with vitamin K1 antagonists are largely derived from case series employing empirical dosing regimens with vitamin K1 and prothrombin complex concentrate...

    Authors: Marzia Angelo, Bernhard Gutmann, Michele Adami, Bernd Zagler, Anton Zelger, Christoph Pechlaner and Christian J Wiedermann
    Citation: Thrombosis Journal 2007 5:1
    Content type: Case report Published on:

  6. Benign Intracranial Hypertension (BIH) may be caused, at least in part, by intracranial sinus thrombosis. Thrombosis is normally due to derangements in blood coagulation cascade which may predispose to abnorma...

    Authors: Domenico De Lucia, Marisanta Napolitano, Pierpaolo Di Micco, Alferio Niglio, Andrea Fontanella and Giuseppe Di lorio
    Citation: Thrombosis Journal 2006 4:21
    Content type: Original clinical investigation Published on:

  7. Thrombosis of the ovarian vein is a rare complication which arises classically in the postpartum. We report a case of 24-year-old woman with a history of Behçet's disease, who presented with pelvic and thoraci...

    Authors: Sonia Hammami, Mondher Golli, Faouzi Addad, Chiraz Hafsa, Amira Hamzaoui, Silvia Mahjoub and Amor Gannouni
    Citation: Thrombosis Journal 2006 4:20
    Content type: Case report Published on:

  8. Adhesion of platelets onto immobilized fibrinogen is of importance in initiation and development of thrombosis. According to a recent increase in evidence of a multiple biological property of antithrombin, we ...

    Authors: Robert Loncar, Uwe Kalina, Volker Stoldt, Volker Thomas, Rüdiger E Scharf and Aleksandar Vodovnik
    Citation: Thrombosis Journal 2006 4:19
    Content type: Original basic research Published on:

  9. Platelet-rich plasma (PRP) is an autologous substance with adhesive properties. We aimed at developing and testing the efficacy of a method for PRP preparation in rabbits.

    Authors: Federico Luengo Gimeno, Silvia Gatto, José Ferro, Juan Oscar Croxatto and Juan Eduardo Gallo
    Citation: Thrombosis Journal 2006 4:18
    Content type: Original basic research Published on:

  10. Clinical trials have shown low-molecular weight heparin (LMWH) to be at least as safe and efficacious as unfractionated heparin (UFH) for preventing venous thromboembolism (VTE) in acutely-ill medical inpatients.

    Authors: Lisa J McGarry, Michael E Stokes and David Thompson
    Citation: Thrombosis Journal 2006 4:17
    Content type: Original clinical investigation Published on:

  11. Hyperhomocysteinemia is an important and independent risk factor for vascular disease. About 35% of patients with stroke and 47% of patients with peripheral arterial disease have elevated plasma homocysteine (...

    Authors: Robert Loncar, Barbara T Müller, Reiner B Zotz, Christof Sucker, Wilhelm Sandmann and Rüdiger E Scharf
    Citation: Thrombosis Journal 2006 4:16
    Content type: Original clinical investigation Published on:

  12. Thrombophilia can be defined as a predisposition to form clots inappropriately. Thrombotic events during infancy and childhood are increasingly recognized as a significant source of mortality and morbidity. Th...

    Authors: Salwa Khan and Joseph D Dickerman
    Citation: Thrombosis Journal 2006 4:15
    Content type: Review Published on:

  13. Thrombolytic drugs are widely used for the management of cerebral venous sinus thrombosis patients. Several in vitro models have been developed to study clot lytic activity of thrombolytic drugs, but all of th...

    Authors: Sweta Prasad, Rajpal S Kashyap, Jayant Y Deopujari, Hemant J Purohit, Girdhar M Taori and Hatim F Daginawala
    Citation: Thrombosis Journal 2006 4:14
    Content type: Original basic research Published on:

  14. The clinical response of sepsis to a systemic inflammatory infection may be complicated by disseminated intravascular coagulation or DIC. In order to experimentally study the syndrome of DIC, we aimed for a se...

    Authors: Sjoukje H Slofstra, Hugo ten Cate and C Arnold Spek
    Citation: Thrombosis Journal 2006 4:13
    Content type: Original basic research Published on:

  15. Soluble fibrin (sFn) is a marker for disseminated intravascular coagulation and may have prognostic significance, especially in metastasis. However, a role for sFn in the etiology of metastatic cancer growth h...

    Authors: John P Biggerstaff, Brandy Weidow, Jacqueline Vidosh, Judith Dexheimer, Shonak Patel and Pretesh Patel
    Citation: Thrombosis Journal 2006 4:12
    Content type: Original basic research Published on:

  16. An increased incidence of deep venous thrombosis (DVT) has been described in multiple myeloma (MM). A recently described mechanism of hypercoagulability in cancer patients including MM patients is acquired act...

    Authors: Jiménez-Zepeda Víctor Hugo and Domínguez-Martínez Virginia Jeanet
    Citation: Thrombosis Journal 2006 4:11
    Content type: Original clinical investigation Published on:

  17. There are controversial evidences on the effect of different types and workloads of physical exercise on primary hemostasis. In particular, little is known on the chronic influence of a strenuous and regular a...

    Authors: Giuseppe Lippi, Martina Montagnana, Gian Luca Salvagno, Massimo Franchini and Gian Cesare Guidi
    Citation: Thrombosis Journal 2006 4:10
    Content type: Original clinical investigation Published on:

  18. Previous studies have suggested that exercise in patients with intermittent claudication (IC) may induce a systemic thrombo-inflammatory response. The effect of secondary prevention therapy on this response is...

    Authors: Patrick Collins, Isobel Ford, Bernard Croal, Derek Ball, Michael Greaves, Ewan Macaulay and Julie Brittenden
    Citation: Thrombosis Journal 2006 4:9
    Content type: Original clinical investigation Published on:

  20. Disseminated intravascular coagulation (DIC) is a pathological disturbance of the complex balance between coagulation and anticoagulation that is precipitated by vascular injury, acidosis, endotoxin release an...

    Authors: Rachel Davis-Jackson, Hernan Correa, Ronald Horswell, Halina Sadowska-Krowicka, Kathleen McDonough, Chittaranjan Debata, Renee' Gardner and Duna Penn
    Citation: Thrombosis Journal 2006 4:7
    Content type: Original basic research Published on:

  21. Unfractionated heparin and low molecular weight heparin are the most commonly used antithrombotic and thromboprophylactic agents in hospital practice. Extended out-of-hospital treatment is inconvenient in that...

    Authors: Ehud Arbit, Michael Goldberg, Isabel Gomez-Orellana and Shingai Majuru
    Citation: Thrombosis Journal 2006 4:6
    Content type: Review Published on:

  22. Platelet activation is crucial in normal hemostasis. Using a clotting system free of external tissue factor, we investigated whether activated Factor VII in combination with platelet agonists increased thrombi...

    Authors: Raul Altman, Alejandra Silvia Scazziota, Maria de Lourdes Herrera and Claudio Gonzalez
    Citation: Thrombosis Journal 2006 4:5
    Content type: Original basic research Published on:

  24. Lupus anticoagulants prolong clotting times in phospholipid-dependent coagulation tests. Lupus Ratio assays are integrated tests for lupus anticoagulants that may be based on APTT, RVVT or dPT clotting times. ...

    Authors: Eva M Jacobsen, Elin J Trettenes, Finn Wisløff and Ulrich Abildgaard
    Citation: Thrombosis Journal 2006 4:3
    Content type: Original basic research Published on:

  25. Systemic sclerosis (SSc) is an autoimmune disorder of the connective tissue characterized by widespread vascular lesions and fibrosis. Little is known so far on the activation of the hemostatic and fibrinolyti...

    Authors: Giuseppe Lippi, Alessandro Volpe, Paola Caramaschi, Gian Luca Salvagno, Martina Montagnana and Gian Cesare Guidi
    Citation: Thrombosis Journal 2006 4:2
    Content type: Original clinical investigation Published on:

  26. For patients with a normal coagulation system, who experience serious bleeding, sound evidence for recombinant activated factor VII (rFVIIa) as an effective haemostatic agent is only scarcely available so far ...

    Authors: P Eller, C Pechlaner and CJ Wiedermann
    Citation: Thrombosis Journal 2006 4:1
    Content type: Case report Published on:

  27. Natural disasters, war, and terrorist attacks, have been linked to cardiac mortality. We sought to investigate whether a major financial crisis may impact on the medical management and outcomes of acute corona...

    Authors: Enrique P Gurfinkel, Gerardo E Bozovich, Omar Dabbous, Branco Mautner and Frederick Anderson
    Citation: Thrombosis Journal 2005 3:22
    Content type: Original clinical investigation Published on:

  30. The presence of thrombi in the atherosclerotic and/or aneurysmatic aorta with peripheral arterial embolism is a common scenario. Thrombus formation in a morphologically normal aorta, however, is a rare event. ...

    Authors: Nasser M Malyar, Rolf A Janosi, Zoran Brkovic and Raimund Erbel
    Citation: Thrombosis Journal 2005 3:19
    Content type: Case report Published on:

  31. To investigate the incidence of pulmonary embolism and risk factors for this condition after obstetric and gynecologic surgery, as well as the efficacy of intermittent pneumatic compression.

    Authors: Nao Suzuki, Fumio Kataoka, Atsushi Higashiguchi, Takeshi Hirao, Sachiko Ezawa, Hiroyuki Nomura, Akiyo Tomita, Nobuyuki Susumu and Daisuke Aoki
    Citation: Thrombosis Journal 2005 3:18
    Content type: Original clinical investigation Published on:

  32. Dengue virus infected patients have high plasminogen activator inhibitor type I (PAI-1) plasma concentrations. Whether the insertion/deletion (4G/5G) polymorphism in the promotor region of the PAI-1 gene is as...

    Authors: ATA Mairuhu, TE Setiati, P Koraka, CE Hack, A Leyte, SMH Faradz, H ten Cate, DPM Brandjes, ADME Osterhaus, PH Reitsma and ECM van Gorp
    Citation: Thrombosis Journal 2005 3:17
    Content type: Original clinical investigation Published on:

  33. Thrombin generation assay was developed several years ago to mimic physiological coagulation mechanisms but it had important limitations. Thrombogram-Thrombinoscope assay using a fluorogenic substrate, allows ...

    Authors: Grigoris T Gerotziafas, François Depasse, Joël Busson, Lena Leflem, Ismail Elalamy and Meyer M Samama
    Citation: Thrombosis Journal 2005 3:16
    Content type: Original basic research Published on:

  34. Circulating procoagulant microparticles (MP) are pathogenic markers of enhanced coagulability associated to a variety of disorders and released from stimulated vascular cells. When derived from endothelial cel...

    Authors: O Morel, L Jesel, JM Freyssinet and F Toti
    Citation: Thrombosis Journal 2005 3:15
    Content type: Case report Published on:

  35. Heparin-induced thrombocytopenia (HIT) is the most important and most frequent drug-induced, immune-mediated type of thrombocytopenia. It is associated with significant morbidity and mortality if unrecognized....

    Authors: Massimo Franchini
    Citation: Thrombosis Journal 2005 3:14
    Content type: Review Published on:

  36. Many available data have suggested that hyperhomocysteinaemia, an established independent risk factor for thrombosis (arterial and venous), may be associated with an increased risk of retinal vein occlusion (R...

    Authors: Paola Ferrazzi, Pierpaolo Di Micco, Ilaria Quaglia, Lisa Simona Rossi, Alessandro Giacco Bellatorre, Giorgio Gaspari, Lidia Luciana Rota and Corrado Lodigiani
    Citation: Thrombosis Journal 2005 3:13
    Content type: Original clinical investigation Published on:

  37. The use of mouse models for the study of thrombotic disorders has gained increasing importance. Methods for measurement of coagulation activation in mice are, however, scarce. The primary aim of this study was...

    Authors: Dirkje W Sommeijer, René van Oerle, Pieter H Reitsma, Janneke J Timmerman, Joost CM Meijers, Henri MH Spronk and Hugo ten Cate
    Citation: Thrombosis Journal 2005 3:12
    Content type: Original basic research Published on:

  38. Septic thrombophlebitis is an iatrogenic life-threatening disease associated with use of central venous devices and intravenous (IV) therapy. In cancer patients receiving chemotherapy, vein resection or surgic...

    Authors: Patricia Volkow, Patricia Cornejo-Juárez, Ana Berta Arizpe-Bravo, Jorge García-Méndez, Enrique Baltazares-Lipp and Rogelio Pérez-Padilla
    Citation: Thrombosis Journal 2005 3:11
    Content type: Case report Published on:

  39. To be fully activated platelets are dependent on two positive feedback loops; the formation of thromboxane A2 by cyclooxygenase in the platelets and the release of ADP. We wanted to evaluate the effect of aspirin...

    Authors: Catharina Borna, Eduardo Lazarowski, Catharina van Heusden, Hans Öhlin and David Erlinge
    Citation: Thrombosis Journal 2005 3:10
    Content type: Original clinical investigation Published on:

  40. Intracardiac thrombus in Behçet's disease is an extremely rare manifestation. We report two such cases. A 20-year-old man presented with dyspnoea, cough and haemoptysis. Right heart thrombus associated with pu...

    Authors: Sonia Hammami, Silvia Mahjoub, Khaldoun Ben-Hamda, Radhia Brahem, Habib Gamra and Mohamed Ben Farhat
    Citation: Thrombosis Journal 2005 3:9
    Content type: Case report Published on:

  41. Little information is available from community-based long-term VTE cohort studies to compare the absolute thrombosis risk of established clinical and genetic risk factors.

    Authors: Michael Spannagl, Lothar AJ Heinemann, Thai DoMinh, Anita Assmann, Wolfgang Schramm and Rolf Schürmann
    Citation: Thrombosis Journal 2005 3:8
    Content type: Review Published on:

  43. We report on a 14 year old boy who presented with the symptoms abdominal pain, fever and proteinuria. A hematoma in the region of the right pararenal space was diagnosed. Prothrombin time and activated partial...

    Authors: Patrick Gerner, Michael Heldmann, Peter Borusiak, Vladimir Bures and Stefan Wirth
    Citation: Thrombosis Journal 2005 3:6
    Content type: Case report Published on:

  44. Community-based cohort studies are not available that evaluated the predictive power of both clinical and genetic risk factors for venous thromboembolism (VTE). There is, however, clinical need to forecast the li...

    Authors: Lothar AJ Heinemann, Thai DoMinh, Anita Assmann, Wolfgang Schramm, Rolf Schürmann, Jan Hilpert and Michael Spannagl
    Citation: Thrombosis Journal 2005 3:5
    Content type: Original clinical investigation Published on:

  45. With the growing use of low-molecular-weight heparins (LMWH) for the treatment and prevention of venous thromboembolism (VTE), it is important to provide an evidence-based comparison with unfractionated hepari...

    Authors: Charles FS Locke, John Dooley and Jonathan Gerber
    Citation: Thrombosis Journal 2005 3:4
    Content type: Review Published on:

  46. It is well described that diabetes mellitus is a hypercoagulable state. It is also known that patients with renal dysfunction have impaired platelet aggregation and function. It is not well described how renal...

    Authors: Donald F Brophy, rika J Martin, Todd WB Gehr and Marcus E Carr Jr
    Citation: Thrombosis Journal 2005 3:3
    Content type: Original clinical investigation Published on:

  47. Fibrin D-dimer levels have been advocated as an useful clinical marker of thrombogenesis.

    Authors: Eleni Hatzinikolaou-Kotsakou, Zafirios Kartasis, Dimitrios Tziakas, Dimitrios Stakos, Athanasios Hotidis, Georgios Chalikias, Georgios Bourikas and Dimitrios I Hatseras
    Citation: Thrombosis Journal 2005 3:2
    Content type: Original clinical investigation Published on:

  48. The use of antithrombotic agents and falls are independently associated with an increased risk of hemorrhagic injury. However, few studies have delineated the risk of fall-related hemorrhagic complications in ...

    Authors: Andrew J Bond, Frank J Molnar, Marilyn Li, Marlene Mackey and Malcolm Man-Son-Hing
    Citation: Thrombosis Journal 2005 3:1
    Content type: Original clinical investigation Published on:
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Thrombosis Journal

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